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Dasatinib Resensitizes MAPK Inhibitor Efficacy in Standard-of-Care Relapsed Melanomas.
Rebecca VW, Xiao M, Kossenkov A, Godok T, Brown GS, Fingerman D, Alicea GM, Wei M, Ji H, Bravo J, Chen Y, Fane ME, Villanueva J, Nathanson K, Liu Q, Gopal YNV, Davies MA, Herlyn M. Rebecca VW, et al. Among authors: chen y. bioRxiv [Preprint]. 2023 Jan 21:2023.01.20.524923. doi: 10.1101/2023.01.20.524923. bioRxiv. 2023. PMID: 36711814 Free PMC article. Preprint.
Tumor-infiltrating mast cells are associated with resistance to anti-PD-1 therapy.
Somasundaram R, Connelly T, Choi R, Choi H, Samarkina A, Li L, Gregorio E, Chen Y, Thakur R, Abdel-Mohsen M, Beqiri M, Kiernan M, Perego M, Wang F, Xiao M, Brafford P, Yang X, Xu X, Secreto A, Danet-Desnoyers G, Traum D, Kaestner KH, Huang AC, Hristova D, Wang J, Fukunaga-Kalabis M, Krepler C, Ping-Chen F, Zhou X, Gutierrez A, Rebecca VW, Vonteddu P, Dotiwala F, Bala S, Majumdar S, Dweep H, Wickramasinghe J, Kossenkov AV, Reyes-Arbujas J, Santiago K, Nguyen T, Griss J, Keeney F, Hayden J, Gavin BJ, Weiner D, Montaner LJ, Liu Q, Peiffer L, Becker J, Burton EM, Davies MA, Tetzlaff MT, Muthumani K, Wargo JA, Gabrilovich D, Herlyn M. Somasundaram R, et al. Among authors: chen y. Nat Commun. 2021 Jan 12;12(1):346. doi: 10.1038/s41467-020-20600-7. Nat Commun. 2021. PMID: 33436641 Free PMC article.
Melanoma-intrinsic NR2F6 activity regulates antitumor immunity.
Kim H, Feng Y, Murad R, Pozniak J, Pelz C, Chen Y, Dalal B, Sears R, Sergienko E, Jackson M, Ruppin E, Herlyn M, Harris C, Marine JC, Klepsch V, Baier G, Ronai ZA. Kim H, et al. Among authors: chen y. Sci Adv. 2023 Jul 7;9(27):eadf6621. doi: 10.1126/sciadv.adf6621. Epub 2023 Jul 5. Sci Adv. 2023. PMID: 37406115 Free PMC article.
Diverse clonal fates emerge upon drug treatment of homogeneous cancer cells.
Goyal Y, Busch GT, Pillai M, Li J, Boe RH, Grody EI, Chelvanambi M, Dardani IP, Emert B, Bodkin N, Braun J, Fingerman D, Kaur A, Jain N, Ravindran PT, Mellis IA, Kiani K, Alicea GM, Fane ME, Ahmed SS, Li H, Chen Y, Chai C, Kaster J, Witt RG, Lazcano R, Ingram DR, Johnson SB, Wani K, Dunagin MC, Lazar AJ, Weeraratna AT, Wargo JA, Herlyn M, Raj A. Goyal Y, et al. Among authors: chen y. Nature. 2023 Aug;620(7974):651-659. doi: 10.1038/s41586-023-06342-8. Epub 2023 Jul 19. Nature. 2023. PMID: 37468627 Free PMC article.
A Comprehensive Proteogenomic and Spatial Analysis of Innate and Acquired Resistance of Metastatic Melanoma to Immune Checkpoint Blockade Therapies.
Wei S, Du K, Lan H, Yang Z, Deng Y, Wei Z, Frederick DT, Lee J, Labrie M, Tian T, Moll T, Chen Y, Sullivan RJ, Mills G, Boland GM, Flaherty KT, Liu L, Herlyn M, Zhang G. Wei S, et al. Among authors: chen y. bioRxiv [Preprint]. 2024 Sep 15:2024.09.12.612675. doi: 10.1101/2024.09.12.612675. bioRxiv. 2024. PMID: 39314469 Free PMC article. Preprint.
PD-L1 in Melanoma and Extracellular Vesicles Promotes Local and Regional Immune Suppression through M2-like Macrophage Polarization.
Huang L, Yang J, Zhu J, Wang H, Dong L, Guo Y, Chen Y, Zhang F, Xu DJ, Ou L, Xu JR, Guan L, Doan QD, Fan AY, Zhong W, Ko J, Liang C, Herlyn M, Guo W, Xu X, Liu S. Huang L, et al. Among authors: chen y. Am J Pathol. 2024 Oct 29:S0002-9440(24)00401-2. doi: 10.1016/j.ajpath.2024.09.011. Online ahead of print. Am J Pathol. 2024. PMID: 39481645
Expert consensus on sequential surgery following conversion therapy based on combination of immune checkpoint inhibitors and antiangiogenic targeted drugs for advanced hepatocellular carcinoma (2024 edition).
Tang H, Zhang W, Cao J, Cao Y, Bi X, Zhao H, Zhang Z, Liu Z, Wan T, Lang R, Sun W, Du S, Yang Y, Lu Y, Zeng D, Wu J, Duan B, Lin D, Li F, Meng Q, Zhou J, Xing B, Tian X, Zhu J, Gao J, Hao C, Wang Z, Duan F, Wang Z, Wang M, Liang B, Chen Y, Xu Y, Li K, Li C, Hu M, Wang Z, Cai S, Ji W, Xia N, Zheng W, Wang H, Li G, Zhu Z, Huang Z, Zhang W, Tao K, Liang J, Zhang K, Dai C, Li J, Qiu Q, Guo Y, Wu L, Ding W, Zhu Z, Gu W, Cao J, Wang Z, Tian L, Ding H, Li G, Zeng Y, Wang K, Yang N, Jin H, Chen Y, Yang Y, Xiu D, Yan M, Wang X, Han Q, Jiao S, Tan G, Wang J, Liu L, Song J, Liao J, Zhao H, Li P, Song T, Wang Z, Yuan J, Hu B, Yuan Y, Zhang M, Sun S, Zhang J, Wang W, Wen T, Yang J, Du X, Peng T, Xia F, Liu Z, Niu W, Liang P, Xu J, Zhao X, Zhu M, Wang H, Kuang M, Shen S, Cui X, Zhou J, Liu R, Sun H, Fan J, Chen X, Zhou J, Cai J, Lu S; Professional Committee for Prevention and Control of Hepatobiliary and Pancreatic Diseases of Chinese Preventive Medicine Association; Chinese Society of Liver Cancer, Liver Study Group of Surgery Committee of Beijing Medical Association; Editorial Board of the Chinese Journal of Hepatobiliary Surgery. Tang H, et al. Among authors: chen y. Biosci Trends. 2024 Dec 25. doi: 10.5582/bst.2024.01394. Online ahead of print. Biosci Trends. 2024. PMID: 39721704
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