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Regulated Induced Proximity Targeting Chimeras (RIPTACs): a Novel Heterobifunctional Small Molecule Therapeutic Strategy for Killing Cancer Cells Selectively.
Raina K, Forbes CD, Stronk R, Rappi JP Jr, Eastman KJ, Gerritz SW, Yu X, Li H, Bhardwaj A, Forgione M, Hundt A, King MP, Posner ZM, Denny A, McGovern A, Puleo DE, Garvin E, Chenard R, Zaware N, Mousseau JJ, Macaluso J, Martin M, Bassoli K, Jones K, Garcia M, Howard K, Smith LM, Chen JM, De Leon CA, Hines J, Kayser-Bricker KJ, Crews CM. Raina K, et al. Among authors: bhardwaj a. bioRxiv [Preprint]. 2023 Jan 2:2023.01.01.522436. doi: 10.1101/2023.01.01.522436. bioRxiv. 2023. Update in: Cell Chem Biol. 2024 Aug 15;31(8):1490-1502.e42. doi: 10.1016/j.chembiol.2024.07.005 PMID: 36711980 Free PMC article. Updated. Preprint.
Regulated induced proximity targeting chimeras-RIPTACs-A heterobifunctional small molecule strategy for cancer selective therapies.
Raina K, Forbes CD, Stronk R, Rappi JP Jr, Eastman KJ, Zaware N, Yu X, Li H, Bhardwaj A, Gerritz SW, Forgione M, Hundt A, King MP, Posner ZM, Correia AD, McGovern A, Puleo DE, Chenard R, Mousseau JJ, Vergara JI, Garvin E, Macaluso J, Martin M, Bassoli K, Jones K, Garcia M, Howard K, Yaggi M, Smith LM, Chen JM, Mayfield AB, De Leon CA, Hines J, Kayser-Bricker KJ, Crews CM. Raina K, et al. Among authors: bhardwaj a. Cell Chem Biol. 2024 Aug 15;31(8):1490-1502.e42. doi: 10.1016/j.chembiol.2024.07.005. Epub 2024 Aug 7. Cell Chem Biol. 2024. PMID: 39116881
ATDC binds to KEAP1 to drive NRF2-mediated tumorigenesis and chemoresistance in pancreatic cancer.
Purohit V, Wang L, Yang H, Li J, Ney GM, Gumkowski ER, Vaidya AJ, Wang A, Bhardwaj A, Zhao E, Dolgalev I, Zamperone A, Abel EV, Magliano MPD, Crawford HC, Diolaiti D, Papagiannakopoulos TY, Lyssiotis CA, Simeone DM. Purohit V, et al. Among authors: bhardwaj a. Genes Dev. 2021 Feb 1;35(3-4):218-233. doi: 10.1101/gad.344184.120. Epub 2021 Jan 14. Genes Dev. 2021. PMID: 33446568 Free PMC article.
Level V metastases in node positive oral squamous cell carcinoma - beyond level IIA and III.
Majumdar KS, Kailey VS, Varshney A, Abhinav T, Panuganti A, Usmani SA, Kaul P, Maharaj DD, Singh A, Moideen A, Prasath R, Ravichandran N, Devi NS, Bhardwaj A, Priya M, Malhotra M. Majumdar KS, et al. Among authors: bhardwaj a. ORL J Otorhinolaryngol Relat Spec. 2024 Dec 16:1-15. doi: 10.1159/000543140. Online ahead of print. ORL J Otorhinolaryngol Relat Spec. 2024. PMID: 39681094 Free article.
1,581 results