Protzer U - Search Results

1

Efficient stabilization of therapeutic hepatitis B vaccine components by amino-acid formulation maintains its potential to break immune tolerance.

Sacherl J, Kosinska AD, Kemter K, Kächele M, Laumen SC, Kerth HA, Öz EA, Wolff LS, Su J, Essbauer S, Sutter G, Scholz M, Singethan K, Altrichter J, Protzer U. Sacherl J, et al. Among authors: protzer u. JHEP Rep. 2022 Oct 13;5(2):100603. doi: 10.1016/j.jhepr.2022.100603. eCollection 2023 Feb. JHEP Rep. 2022. PMID: 36714793 Free PMC article.

2

Synergy of therapeutic heterologous prime-boost hepatitis B vaccination with CpG-application to improve immune control of persistent HBV infection.

Kosinska AD, Moeed A, Kallin N, Festag J, Su J, Steiger K, Michel ML, Protzer U, Knolle PA. Kosinska AD, et al. Among authors: protzer u. Sci Rep. 2019 Jul 25;9(1):10808. doi: 10.1038/s41598-019-47149-w. Sci Rep. 2019. PMID: 31346211 Free PMC article.

3

Interferon-induced degradation of the persistent hepatitis B virus cccDNA form depends on ISG20.

Stadler D, Kächele M, Jones AN, Hess J, Urban C, Schneider J, Xia Y, Oswald A, Nebioglu F, Bester R, Lasitschka F, Ringelhan M, Ko C, Chou WM, Geerlof A, van de Klundert MA, Wettengel JM, Schirmacher P, Heikenwälder M, Schreiner S, Bartenschlager R, Pichlmair A, Sattler M, Unger K, Protzer U. Stadler D, et al. Among authors: protzer u. EMBO Rep. 2021 Jun 4;22(6):e49568. doi: 10.15252/embr.201949568. Epub 2021 May 9. EMBO Rep. 2021. PMID: 33969602 Free PMC article.

4

Immunogenicity and Antiviral Response of Therapeutic Hepatitis B Vaccination in a Mouse Model of HBeAg-Negative, Persistent HBV Infection.

Kosinska AD, Festag J, Mück-Häusl M, Festag MM, Asen T, Protzer U. Kosinska AD, et al. Among authors: protzer u. Vaccines (Basel). 2021 Jul 31;9(8):841. doi: 10.3390/vaccines9080841. Vaccines (Basel). 2021. PMID: 34451966 Free PMC article.

5

Mechanistic principles of an ultra-long bovine CDR reveal strategies for antibody design.

Svilenov HL, Sacherl J, Protzer U, Zacharias M, Buchner J. Svilenov HL, et al. Among authors: protzer u. Nat Commun. 2021 Nov 18;12(1):6737. doi: 10.1038/s41467-021-27103-z. Nat Commun. 2021. PMID: 34795299 Free PMC article.

6

Improving Therapeutic Vaccination against Hepatitis B-Insights from Preclinical Models of Immune Therapy against Persistent Hepatitis B Virus Infection.

Knolle PA, Huang LR, Kosinska A, Wohlleber D, Protzer U. Knolle PA, et al. Among authors: protzer u. Vaccines (Basel). 2021 Nov 16;9(11):1333. doi: 10.3390/vaccines9111333. Vaccines (Basel). 2021. PMID: 34835264 Free PMC article. Review.

7

PD-L1 Silencing in Liver Using siRNAs Enhances Efficacy of Therapeutic Vaccination for Chronic Hepatitis B.

Bunse T, Kosinska AD, Michler T, Protzer U. Bunse T, et al. Among authors: protzer u. Biomolecules. 2022 Mar 18;12(3):470. doi: 10.3390/biom12030470. Biomolecules. 2022. PMID: 35327662 Free PMC article.

8

Multimeric ACE2-IgM fusions as broadly active antivirals that potently neutralize SARS-CoV-2 variants.

Svilenov HL, Bester R, Sacherl J, Absmeier R, Peters C, Protzer U, Brockmeyer C, Buchner J. Svilenov HL, et al. Among authors: protzer u. Commun Biol. 2022 Nov 12;5(1):1237. doi: 10.1038/s42003-022-04193-z. Commun Biol. 2022. PMID: 36371561 Free PMC article.

9

Evaluation of the Effect of CD70 Co-Expression on CD8 T Cell Response in Protein-Prime MVA-Boost Vaccination in Mice.

Stephan AS, Kosinska AD, Mück-Häusl M, Muschaweckh A, Jäger C, Röder N, Heikenwälder M, Dembek C, Protzer U. Stephan AS, et al. Among authors: protzer u. Vaccines (Basel). 2023 Jan 21;11(2):245. doi: 10.3390/vaccines11020245. Vaccines (Basel). 2023. PMID: 36851121 Free PMC article.

10

SARS-CoV-2 Productively Infects Human Hepatocytes and Induces Cell Death.

Ko C, Cheng CC, Mistretta D, Ambike S, Sacherl J, Velkov S, Liao BH, Bester R, Gültan M, Polezhaeva O, Herrmann A, Jakwerth CA, Schmidt-Weber CB, Bugert JJ, Wölfel R, Grass V, Essbauer S, Schnepf D, Keppler OT, Vondran FWR, Pichlmair A, Mogler C, Ebert G, Protzer U. Ko C, et al. Among authors: protzer u. J Med Virol. 2025 Jan;97(1):e70156. doi: 10.1002/jmv.70156. J Med Virol. 2025. PMID: 39760326 Free PMC article.

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