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SARS-CoV-2 Productively Infects Human Hepatocytes and Induces Cell Death.
Ko C, Cheng CC, Mistretta D, Ambike S, Sacherl J, Velkov S, Liao BH, Bester R, Gültan M, Polezhaeva O, Herrmann A, Jakwerth CA, Schmidt-Weber CB, Bugert JJ, Wölfel R, Grass V, Essbauer S, Schnepf D, Keppler OT, Vondran FWR, Pichlmair A, Mogler C, Ebert G, Protzer U. Ko C, et al. Among authors: sacherl j. J Med Virol. 2025 Jan;97(1):e70156. doi: 10.1002/jmv.70156. J Med Virol. 2025. PMID: 39760326 Free PMC article.
Efficient stabilization of therapeutic hepatitis B vaccine components by amino-acid formulation maintains its potential to break immune tolerance.
Sacherl J, Kosinska AD, Kemter K, Kächele M, Laumen SC, Kerth HA, Öz EA, Wolff LS, Su J, Essbauer S, Sutter G, Scholz M, Singethan K, Altrichter J, Protzer U. Sacherl J, et al. JHEP Rep. 2022 Oct 13;5(2):100603. doi: 10.1016/j.jhepr.2022.100603. eCollection 2023 Feb. JHEP Rep. 2022. PMID: 36714793 Free PMC article.
Picomolar inhibition of SARS-CoV-2 variants of concern by an engineered ACE2-IgG4-Fc fusion protein.
Svilenov HL, Sacherl J, Reiter A, Wolff LS, Cheng CC, Stern M, Grass V, Feuerherd M, Wachs FP, Simonavicius N, Pippig S, Wolschin F, Keppler OT, Buchner J, Brockmeyer C, Protzer U. Svilenov HL, et al. Among authors: sacherl j. Antiviral Res. 2021 Dec;196:105197. doi: 10.1016/j.antiviral.2021.105197. Epub 2021 Nov 10. Antiviral Res. 2021. PMID: 34774603 Free PMC article.