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Selective Covalent Targeting of Pyruvate Kinase M2 Using Arsenous Warheads.
Wang J, Zhou S, Cheng Y, Cheng L, Qin Y, Zhang Z, Bi A, Xiang H, He X, Tian X, Liu W, Zhang J, Peng C, Zhu Z, Huang M, Li Y, Zhuang G, Tan L. Wang J, et al. Among authors: tan l. J Med Chem. 2023 Feb 23;66(4):2608-2621. doi: 10.1021/acs.jmedchem.2c01563. Epub 2023 Feb 1. J Med Chem. 2023. PMID: 36723914
Development of Selective Covalent Janus Kinase 3 Inhibitors.
Tan L, Akahane K, McNally R, Reyskens KM, Ficarro SB, Liu S, Herter-Sprie GS, Koyama S, Pattison MJ, Labella K, Johannessen L, Akbay EA, Wong KK, Frank DA, Marto JA, Look TA, Arthur JS, Eck MJ, Gray NS. Tan L, et al. J Med Chem. 2015 Aug 27;58(16):6589-606. doi: 10.1021/acs.jmedchem.5b00710. Epub 2015 Aug 18. J Med Chem. 2015. PMID: 26258521 Free PMC article.
Discovery of a cooperative mode of inhibiting RIPK1 kinase.
Meng H, Wu G, Zhao X, Wang A, Li D, Tong Y, Jin T, Cao Y, Shan B, Hu S, Li Y, Pan L, Tian X, Wu P, Peng C, Yuan J, Li G, Tan L, Wang Z, Li Y. Meng H, et al. Among authors: tan l. Cell Discov. 2021 Jun 1;7(1):41. doi: 10.1038/s41421-021-00278-x. Cell Discov. 2021. PMID: 34075030 Free PMC article.
9,953 results