Derbyshire ER - Search Results

1

Discovery of potent Plasmodium falciparum protein kinase 6 (PfPK6) inhibitors with a type II inhibitor pharmacophore.

Ong HW, Truong A, Kwarcinski F, de Silva C, Avalani K, Havener TM, Chirgwin M, Galal KA, Willis C, Krämer A, Liu S, Knapp S, Derbyshire ER, Zutshi R, Drewry DH. Ong HW, et al. Among authors: derbyshire er. Eur J Med Chem. 2023 Mar 5;249:115043. doi: 10.1016/j.ejmech.2022.115043. Epub 2022 Dec 30. Eur J Med Chem. 2023. PMID: 36736152 Free PMC article.

2

Characterization of two different five-coordinate soluble guanylate cyclase ferrous-nitrosyl complexes.

Derbyshire ER, Gunn A, Ibrahim M, Spiro TG, Britt RD, Marletta MA. Derbyshire ER, et al. Biochemistry. 2008 Mar 25;47(12):3892-9. doi: 10.1021/bi7022943. Epub 2008 Feb 27. Biochemistry. 2008. PMID: 18302323 Free PMC article.

3

Current therapies and future possibilities for drug development against liver-stage malaria.

Raphemot R, Posfai D, Derbyshire ER. Raphemot R, et al. Among authors: derbyshire er. J Clin Invest. 2016 Jun 1;126(6):2013-20. doi: 10.1172/JCI82981. Epub 2016 Jun 1. J Clin Invest. 2016. PMID: 27249674 Free PMC article. Review.

4

The crystal structure of the catalytic domain of a eukaryotic guanylate cyclase.

Winger JA, Derbyshire ER, Lamers MH, Marletta MA, Kuriyan J. Winger JA, et al. Among authors: derbyshire er. BMC Struct Biol. 2008 Oct 7;8:42. doi: 10.1186/1472-6807-8-42. BMC Struct Biol. 2008. PMID: 18842118 Free PMC article.

5

Probing domain interactions in soluble guanylate cyclase.

Derbyshire ER, Winter MB, Ibrahim M, Deng S, Spiro TG, Marletta MA. Derbyshire ER, et al. Biochemistry. 2011 May 24;50(20):4281-90. doi: 10.1021/bi200341b. Epub 2011 May 3. Biochemistry. 2011. PMID: 21491957 Free PMC article.

6

Structure and regulation of soluble guanylate cyclase.

Derbyshire ER, Marletta MA. Derbyshire ER, et al. Annu Rev Biochem. 2012;81:533-59. doi: 10.1146/annurev-biochem-050410-100030. Epub 2012 Feb 9. Annu Rev Biochem. 2012. PMID: 22404633 Review.

7

The next opportunity in anti-malaria drug discovery: the liver stage.

Derbyshire ER, Mota MM, Clardy J. Derbyshire ER, et al. PLoS Pathog. 2011 Sep;7(9):e1002178. doi: 10.1371/journal.ppat.1002178. Epub 2011 Sep 22. PLoS Pathog. 2011. PMID: 21966266 Free PMC article. No abstract available.

8

Biochemistry of soluble guanylate cyclase.

Derbyshire ER, Marletta MA. Derbyshire ER, et al. Handb Exp Pharmacol. 2009;(191):17-31. doi: 10.1007/978-3-540-68964-5_2. Handb Exp Pharmacol. 2009. PMID: 19089323 Review.

9

Erratum: A single amino acid residue controls acyltransferase activity in a polyketide synthase from Toxoplasma gondii.

D'Ambrosio HK, Ganley JG, Keeler AM, Derbyshire ER. D'Ambrosio HK, et al. Among authors: derbyshire er. iScience. 2022 Jun 17;25(7):104608. doi: 10.1016/j.isci.2022.104608. eCollection 2022 Jul 15. iScience. 2022. PMID: 35772031 Free PMC article.

10

Soluble guanylate cyclase is activated differently by excess NO and by YC-1: resonance Raman spectroscopic evidence.

Ibrahim M, Derbyshire ER, Soldatova AV, Marletta MA, Spiro TG. Ibrahim M, et al. Among authors: derbyshire er. Biochemistry. 2010 Jun 15;49(23):4864-71. doi: 10.1021/bi100506j. Biochemistry. 2010. PMID: 20459051 Free PMC article.

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