Knudsen ES - Search Results

1

The BET inhibitor/degrader ARV-825 prolongs the growth arrest response to Fulvestrant + Palbociclib and suppresses proliferative recovery in ER-positive breast cancer.

Finnegan RM, Elshazly AM, Patel NH, Tyutyunyk-Massey L, Tran TH, Kumarasamy V, Knudsen ES, Gewirtz DA. Finnegan RM, et al. Among authors: knudsen es. Front Oncol. 2023 Jan 18;12:966441. doi: 10.3389/fonc.2022.966441. eCollection 2022. Front Oncol. 2023. PMID: 36741704 Free PMC article.

2

Real-World Experience among Elderly Metastatic Breast Cancer Patients Treated with CDK4/6 Inhibitor-Based Therapy.

O'Connor TN, Schultz E, Wang J, O'Connor T, Levine E, Knudsen ES, Witkiewicz AK. O'Connor TN, et al. Among authors: knudsen es. Cancers (Basel). 2024 Apr 30;16(9):1749. doi: 10.3390/cancers16091749. Cancers (Basel). 2024. PMID: 38730702 Free PMC article.

3

Pharmacologically targeting KRAS ^G12D in PDAC models: tumor cell intrinsic and extrinsic impact.

Kumarasamy V, Frangou C, Wang J, Wan Y, Dynka A, Rosenheck H, Dey P, Abel EV, Knudsen ES, Witkiewicz AK. Kumarasamy V, et al. Among authors: knudsen es. bioRxiv [Preprint]. 2023 Apr 20:2023.03.18.533261. doi: 10.1101/2023.03.18.533261. bioRxiv. 2023. PMID: 37162905 Free PMC article. Preprint.

4

Cancer takes many paths through G1/S.

Knudsen ES, Witkiewicz AK, Rubin SM. Knudsen ES, et al. Trends Cell Biol. 2024 Aug;34(8):636-645. doi: 10.1016/j.tcb.2023.10.007. Epub 2023 Nov 10. Trends Cell Biol. 2024. PMID: 37953123 Review.

5

Separable Cell Cycle Arrest and Immune Response Elicited through Pharmacological CDK4/6 and MEK Inhibition in RASmut Disease Models.

Wu J, Wang J, O'Connor TN, Tzetzo SL, Gurova KV, Knudsen ES, Witkiewicz AK. Wu J, et al. Among authors: knudsen es. Mol Cancer Ther. 2024 Dec 3;23(12):1801-1814. doi: 10.1158/1535-7163.MCT-24-0369. Mol Cancer Ther. 2024. PMID: 39148328

6

Senescent CAFs Mediate Immunosuppression and Drive Breast Cancer Progression.

Ye J, Baer JM, Faget DV, Morikis VA, Ren Q, Melam A, Delgado AP, Luo X, Bagchi SM, Belle JI, Campos E, Friedman M, Veis DJ, Knudsen ES, Witkiewicz AK, Powers S, Longmore GD, DeNardo DG, Stewart SA. Ye J, et al. Among authors: knudsen es. Cancer Discov. 2024 Jul 1;14(7):1302-1323. doi: 10.1158/2159-8290.CD-23-0426. Cancer Discov. 2024. PMID: 38683161 Free PMC article.

7

The Extracellular Niche and Tumor Microenvironment Enhance KRAS Inhibitor Efficacy in Pancreatic Cancer.

Kumarasamy V, Wang J, Frangou C, Wan Y, Dynka A, Rosenheck H, Dey P, Abel EV, Knudsen ES, Witkiewicz AK. Kumarasamy V, et al. Among authors: knudsen es. Cancer Res. 2024 Apr 1;84(7):1115-1132. doi: 10.1158/0008-5472.CAN-23-2504. Cancer Res. 2024. PMID: 38294344 Free PMC article.

8

Determinants of response to CDK4/6 inhibitors in the real-world setting.

Witkiewicz AK, Schultz E, Wang J, Hamilton D, Levine E, O'Connor T, Knudsen ES. Witkiewicz AK, et al. Among authors: knudsen es. NPJ Precis Oncol. 2023 Sep 13;7(1):90. doi: 10.1038/s41698-023-00438-0. NPJ Precis Oncol. 2023. PMID: 37704753 Free PMC article.

9

PROTAC-mediated CDK degradation differentially impacts cancer cell cycles due to heterogeneity in kinase dependencies.

Kumarasamy V, Gao Z, Zhao B, Jiang B, Rubin SM, Burgess K, Witkiewicz AK, Knudsen ES. Kumarasamy V, et al. Among authors: knudsen es. Br J Cancer. 2023 Oct;129(8):1238-1250. doi: 10.1038/s41416-023-02399-4. Epub 2023 Aug 25. Br J Cancer. 2023. PMID: 37626264 Free PMC article.

10

Retraction Note: Cyclin-dependent kinase 4/6 activity is a critical determinant of pre-replication complex assembly.

Braden WA, McClendon AK, Knudsen ES. Braden WA, et al. Among authors: knudsen es. Oncogene. 2023 Apr;42(16):1332. doi: 10.1038/s41388-023-02663-0. Oncogene. 2023. PMID: 36949240 No abstract available.

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