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Muc2-dependent microbial colonization of the jejunal mucus layer is diet sensitive and confers local resistance to enteric pathogen infection.
Birchenough GMH, Schroeder BO, Sharba S, Arike L, Recktenwald CV, Puértolas-Balint F, Subramani MV, Hansson KT, Yilmaz B, Lindén SK, Bäckhed F, Hansson GC. Birchenough GMH, et al. Among authors: backhed f. Cell Rep. 2023 Feb 28;42(2):112084. doi: 10.1016/j.celrep.2023.112084. Epub 2023 Feb 6. Cell Rep. 2023. PMID: 36753416 Free PMC article.
Microbial-induced meprin β cleavage in MUC2 mucin and a functional CFTR channel are required to release anchored small intestinal mucus.
Schütte A, Ermund A, Becker-Pauly C, Johansson ME, Rodriguez-Pineiro AM, Bäckhed F, Müller S, Lottaz D, Bond JS, Hansson GC. Schütte A, et al. Among authors: backhed f. Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):12396-401. doi: 10.1073/pnas.1407597111. Epub 2014 Aug 11. Proc Natl Acad Sci U S A. 2014. PMID: 25114233 Free PMC article.
The composition of the gut microbiota shapes the colon mucus barrier.
Jakobsson HE, Rodríguez-Piñeiro AM, Schütte A, Ermund A, Boysen P, Bemark M, Sommer F, Bäckhed F, Hansson GC, Johansson ME. Jakobsson HE, et al. Among authors: backhed f. EMBO Rep. 2015 Feb;16(2):164-77. doi: 10.15252/embr.201439263. Epub 2014 Dec 18. EMBO Rep. 2015. PMID: 25525071 Free PMC article.
Normalization of Host Intestinal Mucus Layers Requires Long-Term Microbial Colonization.
Johansson ME, Jakobsson HE, Holmén-Larsson J, Schütte A, Ermund A, Rodríguez-Piñeiro AM, Arike L, Wising C, Svensson F, Bäckhed F, Hansson GC. Johansson ME, et al. Among authors: backhed f. Cell Host Microbe. 2015 Nov 11;18(5):582-92. doi: 10.1016/j.chom.2015.10.007. Epub 2015 Oct 29. Cell Host Microbe. 2015. PMID: 26526499 Free PMC article.
254 results