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Genetic models of cleavage-reduced and soluble TREM2 reveal distinct effects on myelination and microglia function in the cuprizone model.
Beckmann N, Neuhaus A, Zurbruegg S, Volkmer P, Patino C, Joller S, Feuerbach D, Doelemeyer A, Schweizer T, Rudin S, Neumann U, Berth R, Frieauff W, Gasparini F, Shimshek DR. Beckmann N, et al. Among authors: feuerbach d. J Neuroinflammation. 2023 Feb 8;20(1):29. doi: 10.1186/s12974-022-02671-z. J Neuroinflammation. 2023. PMID: 36755323 Free PMC article.
Sustained Trem2 stabilization accelerates microglia heterogeneity and Aβ pathology in a mouse model of Alzheimer's disease.
Dhandapani R, Neri M, Bernhard M, Brzak I, Schweizer T, Rudin S, Joller S, Berth R, Kernen J, Neuhaus A, Waldt A, Cuttat R, Naumann U, Keller CG, Roma G, Feuerbach D, Shimshek DR, Neumann U, Gasparini F, Galimberti I. Dhandapani R, et al. Among authors: feuerbach d. Cell Rep. 2022 May 31;39(9):110883. doi: 10.1016/j.celrep.2022.110883. Cell Rep. 2022. PMID: 35649351 Free article.
73 results