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Page 1
New Insights into Bitopic Orthosteric/Allosteric Ligands of Cannabinoid Receptor Type 2.
Ferrisi R, Polini B, Ricardi C, Gado F, Mohamed KA, Baron G, Faiella S, Poli G, Rapposelli S, Saccomanni G, Aldini G, Chiellini G, Laprairie RB, Manera C, Ortore G. Ferrisi R, et al. Among authors: ortore g. Int J Mol Sci. 2023 Jan 21;24(3):2135. doi: 10.3390/ijms24032135. Int J Mol Sci. 2023. PMID: 36768458 Free PMC article.
Design, Synthesis, and Biological Activity of New CB2 Receptor Ligands: from Orthosteric and Allosteric Modulators to Dualsteric/Bitopic Ligands.
Gado F, Ferrisi R, Polini B, Mohamed KA, Ricardi C, Lucarini E, Carpi S, Domenichini F, Stevenson LA, Rapposelli S, Saccomanni G, Nieri P, Ortore G, Pertwee RG, Ghelardini C, Di Cesare Mannelli L, Chiellini G, Laprairie RB, Manera C. Gado F, et al. Among authors: ortore g. J Med Chem. 2022 Jul 28;65(14):9918-9938. doi: 10.1021/acs.jmedchem.2c00582. Epub 2022 Jul 18. J Med Chem. 2022. PMID: 35849804 Free PMC article.
Design, synthesis and biological evaluation of novel orthosteric-allosteric ligands of the cannabinoid receptor type 2 (CB2R).
Ferrisi R, Gado F, Polini B, Ricardi C, Mohamed KA, Stevenson LA, Ortore G, Rapposelli S, Saccomanni G, Pertwee RG, Laprairie RB, Manera C, Chiellini G. Ferrisi R, et al. Among authors: ortore g. Front Chem. 2022 Sep 27;10:984069. doi: 10.3389/fchem.2022.984069. eCollection 2022. Front Chem. 2022. PMID: 36238097 Free PMC article.
Adenosine receptor modelling. A1/A2a selectivity.
Tuccinardi T, Ortore G, Manera C, Saccomanni G, Martinelli A. Tuccinardi T, et al. Among authors: ortore g. Eur J Med Chem. 2006 Mar;41(3):321-9. doi: 10.1016/j.ejmech.2005.09.011. Epub 2006 Jan 19. Eur J Med Chem. 2006. PMID: 16427161
Machine Learning-Based Virtual Screening for the Identification of Cdk5 Inhibitors.
Di Stefano M, Galati S, Ortore G, Caligiuri I, Rizzolio F, Ceni C, Bertini S, Bononi G, Granchi C, Macchia M, Poli G, Tuccinardi T. Di Stefano M, et al. Among authors: ortore g. Int J Mol Sci. 2022 Sep 13;23(18):10653. doi: 10.3390/ijms231810653. Int J Mol Sci. 2022. PMID: 36142566 Free PMC article.
1,8-Naphthyridin-4-one derivatives as new ligands of A2A adenosine receptors.
Manera C, Betti L, Cavallini T, Giannaccini G, Martinelli A, Ortore G, Saccomanni G, Trincavelli L, Tuccinardi T, Ferrarini PL. Manera C, et al. Among authors: ortore g. Bioorg Med Chem Lett. 2005 Oct 15;15(20):4604-10. doi: 10.1016/j.bmcl.2005.06.064. Bioorg Med Chem Lett. 2005. PMID: 16099648
47 results