Smith FM - Search Results

1

Frataxin-deficient human brain microvascular endothelial cells lose polymerized actin and are paracellularly permeable -implications for blood-brain barrier integrity in Friedreich's Ataxia.

Smith FM, Kosman DJ. Smith FM, et al. bioRxiv [Preprint]. 2023 Feb 10:2023.02.09.527936. doi: 10.1101/2023.02.09.527936. bioRxiv. 2023. Update in: Front Mol Biosci. 2024 Jan 11;10:1299201. doi: 10.3389/fmolb.2023.1299201 PMID: 36798283 Free PMC article. Updated. Preprint.

2

The solute carriers ZIP8 and ZIP14 regulate manganese accumulation in brain microvascular endothelial cells and control brain manganese levels.

Steimle BL, Smith FM, Kosman DJ. Steimle BL, et al. Among authors: smith fm. J Biol Chem. 2019 Dec 13;294(50):19197-19208. doi: 10.1074/jbc.RA119.009371. Epub 2019 Nov 7. J Biol Chem. 2019. PMID: 31699897 Free PMC article.

3

Molecular Defects in Friedreich's Ataxia: Convergence of Oxidative Stress and Cytoskeletal Abnormalities.

Smith FM, Kosman DJ. Smith FM, et al. Front Mol Biosci. 2020 Nov 9;7:569293. doi: 10.3389/fmolb.2020.569293. eCollection 2020. Front Mol Biosci. 2020. PMID: 33263002 Free PMC article. Review.

4

Calcium and the Ca-ATPase SPCA1 modulate plasma membrane abundance of ZIP8 and ZIP14 to regulate Mn(II) uptake in brain microvascular endothelial cells.

Steimle BL, Bailey DK, Smith FM, Rosenblum SL, Kosman DJ. Steimle BL, et al. Among authors: smith fm. J Biol Chem. 2022 Aug;298(8):102211. doi: 10.1016/j.jbc.2022.102211. Epub 2022 Jul 2. J Biol Chem. 2022. PMID: 35787370 Free PMC article.

5

Loss of filamentous actin, tight junction protein expression, and paracellular barrier integrity in frataxin-deficient human brain microvascular endothelial cells-implications for blood-brain barrier physiology in Friedreich's ataxia.

Smith FM, Kosman DJ. Smith FM, et al. Front Mol Biosci. 2024 Jan 11;10:1299201. doi: 10.3389/fmolb.2023.1299201. eCollection 2023. Front Mol Biosci. 2024. PMID: 38274097 Free PMC article.

6

EphA2 regulates vascular permeability and prostate cancer metastasis via modulation of cell junction protein phosphorylation.

Offenhäuser C, Dave KA, Beckett KJ, Smith FM, Jayakody BA, Cooper LT, Agyei-Yeboah H, McCarron JK, Li Y, Bastick K, Al-Ejeh F, Cullen JK, Coulthard MG, Gorman JJ, Boyd AW, Day BW. Offenhäuser C, et al. Among authors: smith fm. Oncogene. 2024 Nov 7. doi: 10.1038/s41388-024-03206-x. Online ahead of print. Oncogene. 2024. PMID: 39511410

7

GATA1-deficient human pluripotent stem cells generate neutrophils with improved antifungal immunity that is mediated by the integrin CD18.

Wagner AS, Smith FM, Bennin DA, Votava JA, Datta R, Giese MA, Zhao W, Skala MC, Fan J, Keller NP, Huttenlocher A. Wagner AS, et al. Among authors: smith fm. bioRxiv [Preprint]. 2024 Oct 11:2024.10.11.617742. doi: 10.1101/2024.10.11.617742. bioRxiv. 2024. PMID: 39416161 Free PMC article. Preprint.

8

Grb7, Grb10 and Grb14, encoding the growth factor receptor-bound 7 family of signalling adaptor proteins have overlapping functions in the regulation of fetal growth and post-natal glucose metabolism.

Moorwood K, Smith FM, Garfield AS, Cowley M, Holt LJ, Daly RJ, Ward A. Moorwood K, et al. Among authors: smith fm. BMC Biol. 2024 Sep 30;22(1):221. doi: 10.1186/s12915-024-02018-5. BMC Biol. 2024. PMID: 39343875 Free PMC article.

9

Imprinted Grb10, encoding growth factor receptor bound protein 10, regulates fetal growth independently of the insulin-like growth factor type 1 receptor (Igf1r) and insulin receptor (Insr) genes.

Moorwood K, Smith FM, Garfield AS, Ward A. Moorwood K, et al. Among authors: smith fm. BMC Biol. 2024 May 30;22(1):127. doi: 10.1186/s12915-024-01926-w. BMC Biol. 2024. PMID: 38816743 Free PMC article.

10

Demystifying controversies in preschool wheeze.

Smith FM, Saglani S. Smith FM, et al. Expert Rev Respir Med. 2023 Jul-Dec;17(11):1023-1031. doi: 10.1080/17476348.2023.2283128. Epub 2023 Dec 26. Expert Rev Respir Med. 2023. PMID: 37979137 Review.

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