Linhard V - Search Results

1

Optimization of the Lead Compound NVP-BHG712 as a Colorectal Cancer Inhibitor.

Tröster A, DiPrima M, Jores N, Kudlinzki D, Sreeramulu S, Gande SL, Linhard V, Ludig D, Schug A, Saxena K, Reinecke M, Heinzlmeir S, Leisegang MS, Wollenhaupt J, Lennartz F, Weiss MS, Kuster B, Tosato G, Schwalbe H. Tröster A, et al. Among authors: linhard v. Chemistry. 2023 Apr 21;29(23):e202203967. doi: 10.1002/chem.202203967. Epub 2023 Mar 22. Chemistry. 2023. PMID: 36799129 Free PMC article.

2

Vinorine synthase from Rauvolfia: the first example of crystallization and preliminary X-ray diffraction analysis of an enzyme of the BAHD superfamily.

Ma X, Koepke J, Bayer A, Linhard V, Fritzsch G, Zhang B, Michel H, Stöckigt J. Ma X, et al. Among authors: linhard v. Biochim Biophys Acta. 2004 Sep 1;1701(1-2):129-32. doi: 10.1016/j.bbapap.2004.06.011. Biochim Biophys Acta. 2004. PMID: 15450182

3

Randomizing the unfolded state of peptides (and proteins) by nearest neighbor interactions between unlike residues.

Toal SE, Kubatova N, Richter C, Linhard V, Schwalbe H, Schweitzer-Stenner R. Toal SE, et al. Among authors: linhard v. Chemistry. 2015 Mar 23;21(13):5173-92. doi: 10.1002/chem.201406539. Epub 2015 Feb 26. Chemistry. 2015. PMID: 25728043

4

Structure and Biophysical Characterization of the S-Adenosylmethionine-dependent O-Methyltransferase PaMTH1, a Putative Enzyme Accumulating during Senescence of Podospora anserina.

Chatterjee D, Kudlinzki D, Linhard V, Saxena K, Schieborr U, Gande SL, Wurm JP, Wöhnert J, Abele R, Rogov VV, Dötsch V, Osiewacz HD, Sreeramulu S, Schwalbe H. Chatterjee D, et al. Among authors: linhard v. J Biol Chem. 2015 Jun 26;290(26):16415-30. doi: 10.1074/jbc.M115.660829. Epub 2015 May 15. J Biol Chem. 2015. PMID: 25979334 Free PMC article.

5

High-resolution crystal structure of cAMP-dependent protein kinase from Cricetulus griseus.

Kudlinzki D, Linhard VL, Saxena K, Sreeramulu S, Gande S, Schieborr U, Dreyer M, Schwalbe H. Kudlinzki D, et al. Acta Crystallogr F Struct Biol Commun. 2015 Aug;71(Pt 8):1088-93. doi: 10.1107/S2053230X1501242X. Epub 2015 Jul 29. Acta Crystallogr F Struct Biol Commun. 2015. PMID: 26249705 Free PMC article.

6

Expression and Purification of EPHA2 Tyrosine Kinase Domain for Crystallographic and NMR Studies.

Gande SL, Saxena K, Sreeramulu S, Linhard V, Kudlinzki D, Heinzlmeir S, Reichert AJ, Skerra A, Kuster B, Schwalbe H. Gande SL, et al. Among authors: linhard v. Chembiochem. 2016 Dec 2;17(23):2257-2263. doi: 10.1002/cbic.201600483. Epub 2016 Nov 9. Chembiochem. 2016. PMID: 27685543

7

Chemical Proteomics and Structural Biology Define EPHA2 Inhibition by Clinical Kinase Drugs.

Heinzlmeir S, Kudlinzki D, Sreeramulu S, Klaeger S, Gande SL, Linhard V, Wilhelm M, Qiao H, Helm D, Ruprecht B, Saxena K, Médard G, Schwalbe H, Kuster B. Heinzlmeir S, et al. Among authors: linhard v. ACS Chem Biol. 2016 Dec 16;11(12):3400-3411. doi: 10.1021/acschembio.6b00709. Epub 2016 Nov 7. ACS Chem Biol. 2016. PMID: 27768280

8

Chemoproteomics-Aided Medicinal Chemistry for the Discovery of EPHA2 Inhibitors.

Heinzlmeir S, Lohse J, Treiber T, Kudlinzki D, Linhard V, Gande SL, Sreeramulu S, Saxena K, Liu X, Wilhelm M, Schwalbe H, Kuster B, Médard G. Heinzlmeir S, et al. Among authors: linhard v. ChemMedChem. 2017 Jun 21;12(12):999-1011. doi: 10.1002/cmdc.201700217. Epub 2017 Jun 12. ChemMedChem. 2017. PMID: 28544567

9

Corrigendum: Randomizing the Unfolded State of Peptides (and Proteins) by Nearest Neighbor Interactions between Unlike Residues.

Toal SE, Kubatova N, Richter C, Linhard V, Schwalbe H, Schweitzer-Stenner R. Toal SE, et al. Among authors: linhard v. Chemistry. 2017 Dec 19;23(71):18084-18087. doi: 10.1002/chem.201705353. Epub 2017 Dec 8. Chemistry. 2017. PMID: 29265638 English. No abstract available.

10

The domain architecture of PtkA, the first tyrosine kinase from Mycobacterium tuberculosis, differs from the conventional kinase architecture.

Niesteruk A, Jonker HRA, Richter C, Linhard V, Sreeramulu S, Schwalbe H. Niesteruk A, et al. Among authors: linhard v. J Biol Chem. 2018 Jul 27;293(30):11823-11836. doi: 10.1074/jbc.RA117.000120. Epub 2018 Jun 8. J Biol Chem. 2018. PMID: 29884774 Free PMC article.

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