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Functionalized Phenylbenzamides Inhibit Aquaporin-4 Reducing Cerebral Edema and Improving Outcome in Two Models of CNS Injury.
Farr GW, Hall CH, Farr SM, Wade R, Detzel JM, Adams AG, Buch JM, Beahm DL, Flask CA, Xu K, LaManna JC, McGuirk PR, Boron WF, Pelletier MF. Farr GW, et al. Among authors: mcguirk pr. Neuroscience. 2019 Apr 15;404:484-498. doi: 10.1016/j.neuroscience.2019.01.034. Epub 2019 Feb 7. Neuroscience. 2019. PMID: 30738082 Free PMC article.
The aquaporin-4 inhibitor AER-271 blocks acute cerebral edema and improves early outcome in a pediatric model of asphyxial cardiac arrest.
Wallisch JS, Janesko-Feldman K, Alexander H, Jha RM, Farr GW, McGuirk PR, Kline AE, Jackson TC, Pelletier MF, Clark RSB, Kochanek PM, Manole MD. Wallisch JS, et al. Among authors: mcguirk pr. Pediatr Res. 2019 Mar;85(4):511-517. doi: 10.1038/s41390-018-0215-5. Epub 2018 Oct 26. Pediatr Res. 2019. PMID: 30367162 Free PMC article.
New quinolone compounds from Pseudonocardia sp. with selective and potent anti-Helicobacter pylori activity: taxonomy of producing strain, fermentation, isolation, structural elucidation and biological activities.
Dekker KA, Inagaki T, Gootz TD, Huang LH, Kojima Y, Kohlbrenner WE, Matsunaga Y, McGuirk PR, Nomura E, Sakakibara T, Sakemi S, Suzuki Y, Yamauchi Y, Kojima N. Dekker KA, et al. Among authors: mcguirk pr. J Antibiot (Tokyo). 1998 Feb;51(2):145-52. doi: 10.7164/antibiotics.51.145. J Antibiot (Tokyo). 1998. PMID: 9544935 Free article.
Assays to detect and characterize human immunodeficiency virus type 1 (HIV-1) receptor antagonists, compounds that inhibit binding of the HIV-1 surface glycoprotein, gp120, to the CD4 receptor on human T lymphocytes.
Clancy J, Tait-Kamradt A, Petitpas J, Manousos M, McGuirk PR, Subashi T, Watts P, Wondrack L. Clancy J, et al. Among authors: mcguirk pr. Antimicrob Agents Chemother. 1994 Sep;38(9):2008-13. doi: 10.1128/AAC.38.9.2008. Antimicrob Agents Chemother. 1994. PMID: 7811011 Free PMC article.
18 results