Cheng F - Search Results

1

MBOAT7-driven lysophosphatidylinositol acylation in adipocytes contributes to systemic glucose homeostasis.

Massey WJ, Varadharajan V, Banerjee R, Brown AL, Horak AJ, Hohe RC, Jung BM, Qiu Y, Chan ER, Pan C, Zhang R, Allende DS, Willard B, Cheng F, Lusis AJ, Brown JM. Massey WJ, et al. Among authors: cheng f. J Lipid Res. 2023 Apr;64(4):100349. doi: 10.1016/j.jlr.2023.100349. Epub 2023 Feb 18. J Lipid Res. 2023. PMID: 36806709 Free PMC article.

2

Artificial intelligence for drug discovery and development in Alzheimer's disease.

Qiu Y, Cheng F. Qiu Y, et al. Among authors: cheng f. Curr Opin Struct Biol. 2024 Apr;85:102776. doi: 10.1016/j.sbi.2024.102776. Epub 2024 Feb 8. Curr Opin Struct Biol. 2024. PMID: 38335558 Free article. Review.

3

Systematic characterization of multi-omics landscape between gut microbial metabolites and GPCRome in Alzheimer's disease.

Qiu Y, Hou Y, Gohel D, Zhou Y, Xu J, Bykova M, Yang Y, Leverenz JB, Pieper AA, Nussinov R, Caldwell JZK, Brown JM, Cheng F. Qiu Y, et al. Among authors: cheng f. Cell Rep. 2024 May 28;43(5):114128. doi: 10.1016/j.celrep.2024.114128. Epub 2024 Apr 21. Cell Rep. 2024. PMID: 38652661 Free article.

4

A deep learning framework combining molecular image and protein structural representations identifies candidate drugs for pain.

Yang Y, Qiu Y, Hu J, Rosen-Zvi M, Guan Q, Cheng F. Yang Y, et al. Among authors: cheng f. Cell Rep Methods. 2024 Oct 21;4(10):100865. doi: 10.1016/j.crmeth.2024.100865. Epub 2024 Sep 27. Cell Rep Methods. 2024. PMID: 39341201 Free PMC article.

5

Graph embedding and Gaussian mixture variational autoencoder network for end-to-end analysis of single-cell RNA sequencing data.

Xu J, Xu J, Meng Y, Lu C, Cai L, Zeng X, Nussinov R, Cheng F. Xu J, et al. Among authors: cheng f. Cell Rep Methods. 2023 Jan 5;3(1):100382. doi: 10.1016/j.crmeth.2022.100382. eCollection 2023 Jan 23. Cell Rep Methods. 2023. PMID: 36814845 Free PMC article.

6

Editorial overview: Artificial intelligence (AI) methodologies in structural biology.

Cheng F, Tuncbag N. Cheng F, et al. Curr Opin Struct Biol. 2022 Jun;74:102387. doi: 10.1016/j.sbi.2022.102387. Epub 2022 May 16. Curr Opin Struct Biol. 2022. PMID: 35589509 No abstract available.

7

A comprehensive SARS-CoV-2-human protein-protein interactome network identifies pathobiology and host-targeting therapies for COVID-19.

Zhou Y, Liu Y, Gupta S, Paramo MI, Hou Y, Mao C, Luo Y, Judd J, Wierbowski S, Bertolotti M, Nerkar M, Jehi L, Drayman N, Nicolaescu V, Gula H, Tay S, Randall G, Lis JT, Feschotte C, Erzurum SC, Cheng F, Yu H. Zhou Y, et al. Among authors: cheng f. Res Sq [Preprint]. 2022 Jun 7:rs.3.rs-1354127. doi: 10.21203/rs.3.rs-1354127/v2. Res Sq. 2022. Update in: Nat Biotechnol. 2023 Jan;41(1):128-139. doi: 10.1038/s41587-022-01474-0 PMID: 35677070 Free PMC article. Updated. Preprint.

8

Interpretable deep learning translation of GWAS and multi-omics findings to identify pathobiology and drug repurposing in Alzheimer's disease.

Xu J, Mao C, Hou Y, Luo Y, Binder JL, Zhou Y, Bekris LM, Shin J, Hu M, Wang F, Eng C, Oprea TI, Flanagan ME, Pieper AA, Cummings J, Leverenz JB, Cheng F. Xu J, et al. Among authors: cheng f. Cell Rep. 2022 Nov 29;41(9):111717. doi: 10.1016/j.celrep.2022.111717. Cell Rep. 2022. PMID: 36450252 Free PMC article.

9

Microglial immunometabolism endophenotypes contribute to sex difference in Alzheimer's disease.

Hou Y, Caldwell JZK, Lathia JD, Leverenz JB, Pieper AA, Cummings J, Cheng F. Hou Y, et al. Among authors: cheng f. Alzheimers Dement. 2024 Feb;20(2):1334-1349. doi: 10.1002/alz.13546. Epub 2023 Nov 20. Alzheimers Dement. 2024. PMID: 37985399 Free PMC article.

10

Ras, RhoA, and vascular pharmacology in neurodevelopment and aging.

Nussinov R, Jang H, Cheng F. Nussinov R, et al. Among authors: cheng f. Neurochem Int. 2024 Dec;181:105883. doi: 10.1016/j.neuint.2024.105883. Epub 2024 Oct 18. Neurochem Int. 2024. PMID: 39427854 Review.

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