Dhe-Paganon S - Search Results

1

Depletion of creatine phosphagen energetics with a covalent creatine kinase inhibitor.

Darabedian N, Ji W, Fan M, Lin S, Seo HS, Vinogradova EV, Yaron TM, Mills EL, Xiao H, Senkane K, Huntsman EM, Johnson JL, Che J, Cantley LC, Cravatt BF, Dhe-Paganon S, Stegmaier K, Zhang T, Gray NS, Chouchani ET. Darabedian N, et al. Nat Chem Biol. 2023 Jul;19(7):815-824. doi: 10.1038/s41589-023-01273-x. Epub 2023 Feb 23. Nat Chem Biol. 2023. PMID: 36823351 Free PMC article.

2

DNA methyl transferase 1: regulatory mechanisms and implications in health and disease.

Dhe-Paganon S, Syeda F, Park L. Dhe-Paganon S, et al. Int J Biochem Mol Biol. 2011;2(1):58-66. Epub 2011 Jan 30. Int J Biochem Mol Biol. 2011. PMID: 21969122 Free PMC article.

3

A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.

Sheng Y, Hong JH, Doherty R, Srikumar T, Shloush J, Avvakumov GV, Walker JR, Xue S, Neculai D, Wan JW, Kim SK, Arrowsmith CH, Raught B, Dhe-Paganon S. Sheng Y, et al. Mol Cell Proteomics. 2012 Aug;11(8):329-41. doi: 10.1074/mcp.O111.013706. Epub 2012 Apr 10. Mol Cell Proteomics. 2012. PMID: 22496338 Free PMC article.

4

Mechanism of mevalonate pyrophosphate decarboxylase: evidence for a carbocationic transition state.

Dhe-Paganon S, Magrath J, Abeles RH. Dhe-Paganon S, et al. Biochemistry. 1994 Nov 15;33(45):13355-62. doi: 10.1021/bi00249a023. Biochemistry. 1994. PMID: 7947744

5

Protein aggregates are recruited to aggresome by histone deacetylase 6 via unanchored ubiquitin C termini.

Ouyang H, Ali YO, Ravichandran M, Dong A, Qiu W, MacKenzie F, Dhe-Paganon S, Arrowsmith CH, Zhai RG. Ouyang H, et al. J Biol Chem. 2012 Jan 20;287(4):2317-27. doi: 10.1074/jbc.M111.273730. Epub 2011 Nov 8. J Biol Chem. 2012. PMID: 22069321 Free PMC article.

6

Identification of NAE Inhibitors Exhibiting Potent Activity in Leukemia Cells: Exploring the Structural Determinants of NAE Specificity.

Lukkarila JL, da Silva SR, Ali M, Shahani VM, Xu GW, Berman J, Roughton A, Dhe-Paganon S, Schimmer AD, Gunning PT. Lukkarila JL, et al. ACS Med Chem Lett. 2011 May 16;2(8):577-82. doi: 10.1021/ml2000615. eCollection 2011 Aug 11. ACS Med Chem Lett. 2011. PMID: 24900352 Free PMC article.

7

UHRF1 Links the Histone code and DNA Methylation to ensure Faithful Epigenetic Memory Inheritance.

Bronner C, Fuhrmann G, Chédin FL, Macaluso M, Dhe-Paganon S. Bronner C, et al. Genet Epigenet. 2010 Jan 14;2009(2):29-36. Genet Epigenet. 2010. PMID: 21643543 Free PMC article.

8

Two new substrates in insulin signaling, IRS5/DOK4 and IRS6/DOK5.

Cai D, Dhe-Paganon S, Melendez PA, Lee J, Shoelson SE. Cai D, et al. J Biol Chem. 2003 Jul 11;278(28):25323-30. doi: 10.1074/jbc.M212430200. Epub 2003 May 1. J Biol Chem. 2003. PMID: 12730241 Free article.

9

Autoregulation by the juxtamembrane region of the human ephrin receptor tyrosine kinase A3 (EphA3).

Davis TL, Walker JR, Loppnau P, Butler-Cole C, Allali-Hassani A, Dhe-Paganon S. Davis TL, et al. Structure. 2008 Jun;16(6):873-84. doi: 10.1016/j.str.2008.03.008. Structure. 2008. PMID: 18547520 Free article.

10

Crystal structure of the tyrosine phosphatase SHP-2.

Hof P, Pluskey S, Dhe-Paganon S, Eck MJ, Shoelson SE. Hof P, et al. Cell. 1998 Feb 20;92(4):441-50. doi: 10.1016/s0092-8674(00)80938-1. Cell. 1998. PMID: 9491886 Free article.

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