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A hyper-quiescent chromatin state formed during aging is reversed by regeneration.
Yang N, Occean JR, Melters DP, Shi C, Wang L, Stransky S, Doyle ME, Cui CY, Delannoy M, Fan J, Slama E, Egan JM, De S, Cunningham SC, de Cabo R, Sidoli S, Dalal Y, Sen P. Yang N, et al. Among authors: fan j. bioRxiv [Preprint]. 2023 Feb 15:2023.02.14.528512. doi: 10.1101/2023.02.14.528512. bioRxiv. 2023. Update in: Mol Cell. 2023 May 18;83(10):1659-1676.e11. doi: 10.1016/j.molcel.2023.04.005. PMID: 36824822 Free PMC article. Updated. Preprint.
A BDNF-TrkB autocrine loop enhances senescent cell viability.
Anerillas C, Herman AB, Munk R, Garrido A, Lam KG, Payea MJ, Rossi M, Tsitsipatis D, Martindale JL, Piao Y, Mazan-Mamczarz K, Fan J, Cui CY, De S, Abdelmohsen K, de Cabo R, Gorospe M. Anerillas C, et al. Among authors: fan j. Nat Commun. 2022 Oct 20;13(1):6228. doi: 10.1038/s41467-022-33709-8. Nat Commun. 2022. PMID: 36266274 Free PMC article.
Author Correction: A BDNF-TrkB autocrine loop enhances senescent cell viability.
Anerillas C, Herman AB, Munk R, Garrido A, Lam KG, Payea MJ, Rossi M, Tsitsipatis D, Martindale JL, Piao Y, Mazan-Mamczarz K, Fan J, Cui CY, De S, Abdelmohsen K, de Cabo R, Gorospe M. Anerillas C, et al. Among authors: fan j. Nat Commun. 2022 Dec 7;13(1):7540. doi: 10.1038/s41467-022-35154-z. Nat Commun. 2022. PMID: 36477003 Free PMC article. No abstract available.
Transcriptomic analysis of human ALS skeletal muscle reveals a disease-specific pattern of dysregulated circRNAs.
Tsitsipatis D, Mazan-Mamczarz K, Si Y, Herman AB, Yang JH, Guha A, Piao Y, Fan J, Martindale JL, Munk R, Yang X, De S, Singh BK, Ho R, Gorospe M, King PH. Tsitsipatis D, et al. Among authors: fan j. Aging (Albany NY). 2022 Dec 30;14(24):9832-9859. doi: 10.18632/aging.204450. Epub 2022 Dec 30. Aging (Albany NY). 2022. PMID: 36585921 Free PMC article.
Gene body DNA hydroxymethylation restricts the magnitude of transcriptional changes during aging.
Occean JR, Yang N, Sun Y, Dawkins MS, Munk R, Belair C, Dar S, Anerillas C, Wang L, Shi C, Dunn C, Bernier M, Price NL, Kim JS, Cui CY, Fan J, Bhattacharyya M, De S, Maragkakis M, deCabo R, Sidoli S, Sen P. Occean JR, et al. Among authors: fan j. bioRxiv [Preprint]. 2024 Jul 3:2023.02.15.528714. doi: 10.1101/2023.02.15.528714. bioRxiv. 2024. Update in: Nat Commun. 2024 Jul 28;15(1):6357. doi: 10.1038/s41467-024-50725-y. PMID: 36824863 Free PMC article. Updated. Preprint.
DPP4 inhibition impairs senohemostasis to improve plaque stability in atherosclerotic mice.
Herman AB, Tsitsipatis D, Anerillas C, Mazan-Mamczarz K, Carr AE, Gregg JM, Wang M, Zhang J, Michel M, Henry-Smith CA, Harris SC, Munk R, Martindale JL, Piao Y, Fan J, Mattison JA, De S, Abdelmohsen K, Maul RW, Tanaka T, Moore AZ, DeMouth ME, Sidoli S, Ferrucci L, Liu Y, de Cabo R, Lakatta EG, Gorospe M. Herman AB, et al. Among authors: fan j. J Clin Invest. 2023 Jun 15;133(12):e165933. doi: 10.1172/JCI165933. J Clin Invest. 2023. PMID: 37097759 Free PMC article.
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