Rowland Yeo K - Search Results

1

PBPK modeling of ivermectin-Considerations for the purpose of developing alternative routes to optimize its safety profile.

Rowland Yeo K, Wesche D. Rowland Yeo K, et al. CPT Pharmacometrics Syst Pharmacol. 2023 May;12(5):598-609. doi: 10.1002/psp4.12950. Epub 2023 Mar 15. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 36840414 Free PMC article. Review.

2

Lipid lowering in patients with diabetes mellitus: what coronary heart disease risk threshold should be used?

Rowland Yeo K, Yeo WW. Rowland Yeo K, et al. Among authors: yeo ww. Heart. 2002 May;87(5):423-7. doi: 10.1136/heart.87.5.423. Heart. 2002. PMID: 11997409 Free PMC article.

3

Prediction of in vivo drug clearance from in vitro data. II: potential inter-ethnic differences.

Inoue S, Howgate EM, Rowland-Yeo K, Shimada T, Yamazaki H, Tucker GT, Rostami-Hodjegan A. Inoue S, et al. Among authors: rowland yeo k. Xenobiotica. 2006 Jun;36(6):499-513. doi: 10.1080/00498250600683262. Xenobiotica. 2006. PMID: 16865818

4

Using human recombinant UDP-glucuronosyltransferase isoforms and a relative activity factor approach to model total body clearance of laropiprant (MK-0524) in humans.

Gibson CR, Lu P, Maciolek C, Wudarski C, Barter Z, Rowland-Yeo K, Stroh M, Lai E, Nicoll-Griffith DA. Gibson CR, et al. Among authors: rowland yeo k. Xenobiotica. 2013 Dec;43(12):1027-36. doi: 10.3109/00498254.2013.791761. Epub 2013 May 3. Xenobiotica. 2013. PMID: 23641955 Clinical Trial.

5

The impact of experimental design on assessing mechanism-based inactivation of CYP2D6 by MDMA (Ecstasy).

Van LM, Heydari A, Yang J, Hargreaves J, Rowland-Yeo K, Lennard MS, Tucker GT, Rostami-Hodjegan A. Van LM, et al. Among authors: rowland yeo k. J Psychopharmacol. 2006 Nov;20(6):834-41. doi: 10.1177/0269881106062902. Epub 2006 Feb 14. J Psychopharmacol. 2006. PMID: 16478752

6

Assessment of algorithms for predicting drug-drug interactions via inhibition mechanisms: comparison of dynamic and static models.

Guest EJ, Rowland-Yeo K, Rostami-Hodjegan A, Tucker GT, Houston JB, Galetin A. Guest EJ, et al. Among authors: rowland yeo k. Br J Clin Pharmacol. 2011 Jan;71(1):72-87. doi: 10.1111/j.1365-2125.2010.03799.x. Br J Clin Pharmacol. 2011. PMID: 21143503 Free PMC article.

7

Evidence that serine 304 is not a key ligand-binding residue in the active site of cytochrome P450 2D6.

Ellis SW, Hayhurst GP, Lightfoot T, Smith G, Harlow J, Rowland-Yeo K, Larsson C, Mahling J, Lim CK, Wolf CR, Blackburn MG, Lennard MS, Tucker GT. Ellis SW, et al. Among authors: rowland yeo k. Biochem J. 2000 Feb 1;345 Pt 3(Pt 3):565-71. Biochem J. 2000. PMID: 10642515 Free PMC article.

8

A critical evaluation of the experimental design of studies of mechanism based enzyme inhibition, with implications for in vitro-in vivo extrapolation.

Ghanbari F, Rowland-Yeo K, Bloomer JC, Clarke SE, Lennard MS, Tucker GT, Rostami-Hodjegan A. Ghanbari F, et al. Among authors: rowland yeo k. Curr Drug Metab. 2006 Apr;7(3):315-34. doi: 10.2174/138920006776359293. Curr Drug Metab. 2006. PMID: 16611025 Review.

9

Prediction of metabolic drug clearance in humans: in vitro-in vivo extrapolation vs allometric scaling.

Shiran MR, Proctor NJ, Howgate EM, Rowland-Yeo K, Tucker GT, Rostami-Hodjegan A. Shiran MR, et al. Among authors: rowland yeo k. Xenobiotica. 2006 Jul;36(7):567-80. doi: 10.1080/00498250600761662. Xenobiotica. 2006. PMID: 16864504

10

Evaluation of the novel in vitro systems for hepatic drug clearance and assessment of their predictive utility.

Houston JB, Rowland-Yeo K, Zanelli U. Houston JB, et al. Among authors: rowland yeo k. Toxicol In Vitro. 2012 Dec;26(8):1265-71. doi: 10.1016/j.tiv.2011.12.016. Epub 2012 Jan 8. Toxicol In Vitro. 2012. PMID: 22244922

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