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Page 1
The emerging roles of bacterial proteases in intestinal diseases.
Caminero A, Guzman M, Libertucci J, Lomax AE. Caminero A, et al. Among authors: lomax ae. Gut Microbes. 2023 Jan-Dec;15(1):2181922. doi: 10.1080/19490976.2023.2181922. Gut Microbes. 2023. PMID: 36843008 Free PMC article. Review.
Protease-Mediated Suppression of DRG Neuron Excitability by Commensal Bacteria.
Sessenwein JL, Baker CC, Pradhananga S, Maitland ME, Petrof EO, Allen-Vercoe E, Noordhof C, Reed DE, Vanner SJ, Lomax AE. Sessenwein JL, et al. Among authors: lomax ae. J Neurosci. 2017 Nov 29;37(48):11758-11768. doi: 10.1523/JNEUROSCI.1672-17.2017. Epub 2017 Oct 31. J Neurosci. 2017. PMID: 29089436 Free PMC article.
Bacterial modulation of visceral sensation: mediators and mechanisms.
Lomax AE, Pradhananga S, Sessenwein JL, O'Malley D. Lomax AE, et al. Am J Physiol Gastrointest Liver Physiol. 2019 Sep 1;317(3):G363-G372. doi: 10.1152/ajpgi.00052.2019. Epub 2019 Jul 10. Am J Physiol Gastrointest Liver Physiol. 2019. PMID: 31290688 Free article. Review.
Agonist that activates the µ-opioid receptor in acidified microenvironments inhibits colitis pain without side effects.
Jiménez-Vargas NN, Yu Y, Jensen DD, Bok DD, Wisdom M, Latorre R, Lopez C, Jaramillo-Polanco JO, Degro C, Guzman-Rodriguez M, Tsang Q, Snow Z, Schmidt BL, Reed DE, Lomax AE, Margolis KG, Stein C, Bunnett NW, Vanner SJ. Jiménez-Vargas NN, et al. Among authors: lomax ae. Gut. 2022 Apr;71(4):695-704. doi: 10.1136/gutjnl-2021-324070. Epub 2021 Mar 30. Gut. 2022. PMID: 33785555 Free PMC article.
Histamine production by the gut microbiota induces visceral hyperalgesia through histamine 4 receptor signaling in mice.
De Palma G, Shimbori C, Reed DE, Yu Y, Rabbia V, Lu J, Jimenez-Vargas N, Sessenwein J, Lopez-Lopez C, Pigrau M, Jaramillo-Polanco J, Zhang Y, Baerg L, Manzar A, Pujo J, Bai X, Pinto-Sanchez MI, Caminero A, Madsen K, Surette MG, Beyak M, Lomax AE, Verdu EF, Collins SM, Vanner SJ, Bercik P. De Palma G, et al. Among authors: lomax ae. Sci Transl Med. 2022 Jul 27;14(655):eabj1895. doi: 10.1126/scitranslmed.abj1895. Epub 2022 Jul 27. Sci Transl Med. 2022. PMID: 35895832
Changes in signalling from faecal neuroactive metabolites following dietary modulation of IBS pain.
Tuck CJ, Abu Omar A, De Palma G, Osman S, Jiménez-Vargas NN, Yu Y, Bennet SM, Lopez-Lopez C, Jaramillo-Polanco JO, Baker CC, Bennett AS, Guzman-Rodriguez M, Tsang Q, Alward T, Rolland S, Morissette C, Verdu EF, Bercik P, Vanner SJ, Lomax AE, Reed DE. Tuck CJ, et al. Among authors: lomax ae. Gut. 2022 Dec 13:gutjnl-2022-327260. doi: 10.1136/gutjnl-2022-327260. Online ahead of print. Gut. 2022. PMID: 36591617
Protease-Induced Excitation of Dorsal Root Ganglion Neurons in Response to Acute Perturbation of the Gut Microbiota Is Associated With Visceral and Somatic Hypersensitivity.
Baker CC, Sessenwein JL, Wood HM, Yu Y, Tsang Q, Alward TA, Jimenez Vargas NN, Omar AA, McDonnel A, Segal JP, Sjaarda CP, Bunnett NW, Schmidt BL, Caminero A, Boev N, Bannerman CA, Ghasemlou N, Sheth PM, Vanner SJ, Reed DE, Lomax AE. Baker CC, et al. Among authors: lomax ae. Cell Mol Gastroenterol Hepatol. 2024;18(4):101334. doi: 10.1016/j.jcmgh.2024.03.006. Epub 2024 Mar 16. Cell Mol Gastroenterol Hepatol. 2024. PMID: 38494056 Free PMC article.
77 results