Badenhorst CPS - Search Results

1

Enlightening the Path to Protein Engineering: Chemoselective Turn-On Probes for High-Throughput Screening of Enzymatic Activity.

Hecko S, Schiefer A, Badenhorst CPS, Fink MJ, Mihovilovic MD, Bornscheuer UT, Rudroff F. Hecko S, et al. Among authors: badenhorst cps. Chem Rev. 2023 Mar 22;123(6):2832-2901. doi: 10.1021/acs.chemrev.2c00304. Epub 2023 Feb 28. Chem Rev. 2023. PMID: 36853077 Free PMC article. Review.

2

Characterisation of the influence of genetic variations on the enzyme activity of a recombinant human glycine N-acyltransferase.

van der Sluis R, Badenhorst CP, van der Westhuizen FH, van Dijk AA. van der Sluis R, et al. Gene. 2013 Feb 25;515(2):447-53. doi: 10.1016/j.gene.2012.12.003. Epub 2012 Dec 10. Gene. 2013. PMID: 23237781

3

Conservation of the coding regions of the glycine N-acyltransferase gene further suggests that glycine conjugation is an essential detoxification pathway.

van der Sluis R, Badenhorst CP, Erasmus E, van Dyk E, van der Westhuizen FH, van Dijk AA. van der Sluis R, et al. Gene. 2015 Oct 15;571(1):126-34. doi: 10.1016/j.gene.2015.06.081. Epub 2015 Jul 3. Gene. 2015. PMID: 26149650

4

Enzymatic characterization and elucidation of the catalytic mechanism of a recombinant bovine glycine N-acyltransferase.

Badenhorst CP, Jooste M, van Dijk AA. Badenhorst CP, et al. Drug Metab Dispos. 2012 Feb;40(2):346-52. doi: 10.1124/dmd.111.041657. Epub 2011 Nov 9. Drug Metab Dispos. 2012. PMID: 22071172

5

Getting Momentum: From Biocatalysis to Advanced Synthetic Biology.

Badenhorst CPS, Bornscheuer UT. Badenhorst CPS, et al. Trends Biochem Sci. 2018 Mar;43(3):180-198. doi: 10.1016/j.tibs.2018.01.003. Epub 2018 Feb 6. Trends Biochem Sci. 2018. PMID: 29426712 Review.

6

Sequence-Based Prediction of Promiscuous Acyltransferase Activity in Hydrolases.

Müller H, Becker AK, Palm GJ, Berndt L, Badenhorst CPS, Godehard SP, Reisky L, Lammers M, Bornscheuer UT. Müller H, et al. Among authors: badenhorst cps. Angew Chem Int Ed Engl. 2020 Jul 6;59(28):11607-11612. doi: 10.1002/anie.202003635. Epub 2020 May 11. Angew Chem Int Ed Engl. 2020. PMID: 32243661 Free PMC article.

7

An Ultrasensitive Fluorescence Assay for the Detection of Halides and Enzymatic Dehalogenation.

Aslan-Üzel AS, Beier A, Kovář D, Cziegler C, Padhi SK, Schuiten ED, Dörr M, Böttcher D, Hollmann F, Rudroff F, Mihovilovic MD, Buryška T, Damborský J, Prokop Z, Badenhorst CPS, Bornscheuer UT. Aslan-Üzel AS, et al. Among authors: badenhorst cps. ChemCatChem. 2020 Apr 6;12(7):2032-2039. doi: 10.1002/cctc.201901891. Epub 2020 Jan 31. ChemCatChem. 2020. PMID: 32362951 Free PMC article.

8

Engineering Regioselectivity of a P450 Monooxygenase Enables the Synthesis of Ursodeoxycholic Acid via 7β-Hydroxylation of Lithocholic Acid.

Grobe S, Badenhorst CPS, Bayer T, Hamnevik E, Wu S, Grathwol CW, Link A, Koban S, Brundiek H, Großjohann B, Bornscheuer UT. Grobe S, et al. Among authors: badenhorst cps. Angew Chem Int Ed Engl. 2021 Jan 11;60(2):753-757. doi: 10.1002/anie.202012675. Epub 2020 Nov 12. Angew Chem Int Ed Engl. 2021. PMID: 33085147 Free PMC article.

9

Directed Evolution of a Halide Methyltransferase Enables Biocatalytic Synthesis of Diverse SAM Analogs.

Tang Q, Grathwol CW, Aslan-Üzel AS, Wu S, Link A, Pavlidis IV, Badenhorst CPS, Bornscheuer UT. Tang Q, et al. Among authors: badenhorst cps. Angew Chem Int Ed Engl. 2021 Jan 18;60(3):1524-1527. doi: 10.1002/anie.202013871. Epub 2020 Nov 12. Angew Chem Int Ed Engl. 2021. PMID: 33108827 Free PMC article.

10

Discovery and Design of Family VIII Carboxylesterases as Highly Efficient Acyltransferases.

Müller H, Godehard SP, Palm GJ, Berndt L, Badenhorst CPS, Becker AK, Lammers M, Bornscheuer UT. Müller H, et al. Among authors: badenhorst cps. Angew Chem Int Ed Engl. 2021 Jan 25;60(4):2013-2017. doi: 10.1002/anie.202014169. Epub 2020 Nov 23. Angew Chem Int Ed Engl. 2021. PMID: 33140887 Free PMC article.

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