Veglia G - Search Results

1

Edmond Fischer's kinase legacy: History of the protein kinase inhibitor and protein kinase A.

Taylor SS, Herberg FW, Veglia G, Wu J. Taylor SS, et al. Among authors: veglia g. IUBMB Life. 2023 Apr;75(4):311-323. doi: 10.1002/iub.2714. Epub 2023 Feb 28. IUBMB Life. 2023. PMID: 36855225 Free PMC article.

2

Allosteric cooperativity in protein kinase A.

Masterson LR, Mascioni A, Traaseth NJ, Taylor SS, Veglia G. Masterson LR, et al. Among authors: veglia g. Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):506-11. doi: 10.1073/pnas.0709214104. Epub 2008 Jan 4. Proc Natl Acad Sci U S A. 2008. PMID: 18178622 Free PMC article.

3

Dynamics connect substrate recognition to catalysis in protein kinase A.

Masterson LR, Cheng C, Yu T, Tonelli M, Kornev A, Taylor SS, Veglia G. Masterson LR, et al. Among authors: veglia g. Nat Chem Biol. 2010 Nov;6(11):821-8. doi: 10.1038/nchembio.452. Epub 2010 Oct 3. Nat Chem Biol. 2010. PMID: 20890288 Free PMC article.

4

Dynamically committed, uncommitted, and quenched states encoded in protein kinase A revealed by NMR spectroscopy.

Masterson LR, Shi L, Metcalfe E, Gao J, Taylor SS, Veglia G. Masterson LR, et al. Among authors: veglia g. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6969-74. doi: 10.1073/pnas.1102701108. Epub 2011 Apr 6. Proc Natl Acad Sci U S A. 2011. PMID: 21471451 Free PMC article.

5

Conformational equilibrium of N-myristoylated cAMP-dependent protein kinase A by molecular dynamics simulations.

Cembran A, Masterson LR, McClendon CL, Taylor SS, Gao J, Veglia G. Cembran A, et al. Among authors: veglia g. Biochemistry. 2012 Dec 21;51(51):10186-96. doi: 10.1021/bi301279f. Epub 2012 Dec 12. Biochemistry. 2012. PMID: 23205665 Free PMC article.

6

Synchronous opening and closing motions are essential for cAMP-dependent protein kinase A signaling.

Srivastava AK, McDonald LR, Cembran A, Kim J, Masterson LR, McClendon CL, Taylor SS, Veglia G. Srivastava AK, et al. Among authors: veglia g. Structure. 2014 Dec 2;22(12):1735-1743. doi: 10.1016/j.str.2014.09.010. Epub 2014 Nov 6. Structure. 2014. PMID: 25458836 Free PMC article.

7

Dysfunctional conformational dynamics of protein kinase A induced by a lethal mutant of phospholamban hinder phosphorylation.

Kim J, Masterson LR, Cembran A, Verardi R, Shi L, Gao J, Taylor SS, Veglia G. Kim J, et al. Among authors: veglia g. Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):3716-21. doi: 10.1073/pnas.1502299112. Epub 2015 Mar 9. Proc Natl Acad Sci U S A. 2015. PMID: 25775607 Free PMC article.

8

Mapping the Hydrogen Bond Networks in the Catalytic Subunit of Protein Kinase A Using H/D Fractionation Factors.

Li GC, Srivastava AK, Kim J, Taylor SS, Veglia G. Li GC, et al. Among authors: veglia g. Biochemistry. 2015 Jul 7;54(26):4042-9. doi: 10.1021/acs.biochem.5b00387. Epub 2015 Jun 26. Biochemistry. 2015. PMID: 26030372 Free PMC article.

9

Uncoupling Catalytic and Binding Functions in the Cyclic AMP-Dependent Protein Kinase A.

Kim J, Li G, Walters MA, Taylor SS, Veglia G. Kim J, et al. Among authors: veglia g. Structure. 2016 Mar 1;24(3):353-63. doi: 10.1016/j.str.2015.11.016. Epub 2016 Jan 28. Structure. 2016. PMID: 26833386 Free PMC article.

10

Mutation of a kinase allosteric node uncouples dynamics linked to phosphotransfer.

Ahuja LG, Kornev AP, McClendon CL, Veglia G, Taylor SS. Ahuja LG, et al. Among authors: veglia g. Proc Natl Acad Sci U S A. 2017 Feb 7;114(6):E931-E940. doi: 10.1073/pnas.1620667114. Epub 2017 Jan 23. Proc Natl Acad Sci U S A. 2017. PMID: 28115705 Free PMC article.

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