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Page 1
Alcohol-induced extracellular ASC specks perpetuate liver inflammation and damage in alcohol-associated hepatitis even after alcohol cessation.
de Carvalho Ribeiro M, Iracheta-Vellve A, Babuta M, Calenda CD, Copeland C, Zhuang Y, Lowe PP, Hawryluk D, Catalano D, Cho Y, Barton B, Dasarathy S, McClain C, McCullough AJ, Mitchell MC, Nagy LE, Radaeva S, Lien E, Golenbock DT, Szabo G. de Carvalho Ribeiro M, et al. Among authors: nagy le. Hepatology. 2023 Jul 1;78(1):225-242. doi: 10.1097/HEP.0000000000000298. Epub 2023 Mar 3. Hepatology. 2023. PMID: 36862512
Safety, Pharmacokinetics, and Efficacy Signals of Larsucosterol (DUR-928) in Alcohol-Associated Hepatitis.
Hassanein T, McClain CJ, Vatsalya V, Stein LL, Flamm SL, Martin P, Cave MC, Mitchell M Jr, Barton B, Nagy L, Szabo G, McCullough A, Dasarathy S, Shah J, Blevins C, Scott D, Krebs W, Brown JE, Lin W. Hassanein T, et al. Am J Gastroenterol. 2024 Jan 1;119(1):107-115. doi: 10.14309/ajg.0000000000002275. Epub 2023 Apr 3. Am J Gastroenterol. 2024. PMID: 37011138 Free PMC article.
Randomized trial of anakinra plus zinc vs. prednisone for severe alcohol-associated hepatitis.
Gawrieh S, Dasarathy S, Tu W, Kamath PS, Chalasani NP, McClain CJ, Bataller R, Szabo G, Tang Q, Radaeva S, Barton B, Nagy LE, Shah VH, Sanyal AJ, Mitchell MC; AlcHepNet Investigators. Gawrieh S, et al. Among authors: nagy le. J Hepatol. 2024 May;80(5):684-693. doi: 10.1016/j.jhep.2024.01.031. Epub 2024 Feb 10. J Hepatol. 2024. PMID: 38342441 Clinical Trial.
Acute kidney injury in severe alcohol-associated hepatitis treated with anakinra plus zinc or prednisone.
Patidar KR, Tu W, Cotter TG, Simonetto DA, Asgharpour A, Jan MY, Tang Q, Yu Y, Li Y, Taiwo M, Thevkar Nagesh P, Dasarathy S, Kamath PS, McClain CJ, Chalasani N, Szabo G, Bataller R, Mitchell M, Mehal WZ, Nagy LE, Shah VH, Gawrieh S, Sanyal AJ; AlcHepNet Investigators. Patidar KR, et al. Among authors: nagy le. Hepatology. 2024 Jul 19. doi: 10.1097/HEP.0000000000001019. Online ahead of print. Hepatology. 2024. PMID: 39028887
Acute and chronic alcohol abuse modulate immunity.
Brown LA, Cook RT, Jerrells TR, Kolls JK, Nagy LE, Szabo G, Wands JR, Kovacs EJ. Brown LA, et al. Among authors: nagy le. Alcohol Clin Exp Res. 2006 Sep;30(9):1624-31. doi: 10.1111/j.1530-0277.2006.00195.x. Alcohol Clin Exp Res. 2006. PMID: 16930226
A polygenic risk score for alcohol-associated cirrhosis among heavy drinkers with European ancestry.
Schwantes-An TH, Whitfield JB, Aithal GP, Atkinson SR, Bataller R, Botwin G, Chalasani NP, Cordell HJ, Daly AK, Darlay R, Day CP, Eyer F, Foroud T, Gawrieh S, Gleeson D, Goldman D, Haber PS, Jacquet JM, Lammert CS, Liang T, Liangpunsakul S, Masson S, Mathurin P, Moirand R, McQuillin A, Moreno C, Morgan MY, Mueller S, Müllhaupt B, Nagy LE, Nahon P, Nalpas B, Naveau S, Perney P, Pirmohamed M, Seitz HK, Soyka M, Stickel F, Thompson A, Thursz MR, Trépo E, Morgan TR, Seth D; GenomALC Consortium. Schwantes-An TH, et al. Among authors: nagy le. Hepatol Commun. 2024 May 10;8(6):e0431. doi: 10.1097/HC9.0000000000000431. eCollection 2024 Jun 1. Hepatol Commun. 2024. PMID: 38727677 Free PMC article.
Physiological processes underlying organ injury in alcohol abuse.
Souza-Smith FM, Lang CH, Nagy LE, Bailey SM, Parsons LH, Murray GJ. Souza-Smith FM, et al. Among authors: nagy le. Am J Physiol Endocrinol Metab. 2016 Sep 1;311(3):E605-19. doi: 10.1152/ajpendo.00270.2016. Epub 2016 Jul 19. Am J Physiol Endocrinol Metab. 2016. PMID: 27436613 Free PMC article. Review.
The pyruvate dehydrogenase kinase inhibitor dichloroacetate mitigates alcohol-induced hepatic inflammation and metabolic disturbances in mice.
Wu J, Huang E, McMullen MR, Singh V, Mrdjen M, Bellar A, Wang L, Welch N, Dasarathy J, Dasarathy S, Streem D, Brown JM, Nagy LE. Wu J, et al. Among authors: nagy le. Hepatol Commun. 2024 Nov 29;8(12):e0547. doi: 10.1097/HC9.0000000000000547. eCollection 2024 Dec 1. Hepatol Commun. 2024. PMID: 39621302 Free PMC article.
220 results