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In-vivo and in-silico studies revealed the molecular mechanisms of Colocasia esculenta phenolics as novel chemotherapy against benign prostatic hyperplasia via inhibition of 5α-reductase and α1-adrenoceptor.
Tusubira D, Munezero J, Agu PC, Ajayi CO, Oloro J, Namale N, Ssedyabane F, Nakiguli CK, Adegboyega AE, Aja PM. Tusubira D, et al. Among authors: agu pc. In Silico Pharmacol. 2023 Mar 1;11(1):4. doi: 10.1007/s40203-023-00141-9. eCollection 2023. In Silico Pharmacol. 2023. PMID: 36873908 Free PMC article.
Cucumeropsis mannii seed oil protects against Bisphenol A-induced testicular mitochondrial damages.
Aja PM, Ogwoni HA, Agu PC, Ekpono EU, Awoke JN, Ukachi OU, Orji OU, Ale BA, Nweke CP, Igwenyi IO, Alum EU, Chukwu DC, Offor CE, Asuk AA, Eze ED, Yakubu OE, Akobi JB, Ani OG, Awuchi CG. Aja PM, et al. Among authors: agu pc. Food Sci Nutr. 2023 Feb 7;11(6):2631-2641. doi: 10.1002/fsn3.3260. eCollection 2023 Jun. Food Sci Nutr. 2023. PMID: 37324897 Free PMC article.
Cucumeropsis mannii seed oil ameliorates Bisphenol-A-induced adipokines dysfunctions and dyslipidemia.
Aja PM, Chiadikaobi CD, Agu PC, Ale BA, Ani OG, Ekpono EU, Ogwoni HA, Awoke JN, Ogbu PN, Aja L, Nwite FE, Ukachi OU, Orji OU, Nweke PC, Egwu CO, Ekpono EU, Ewa GO, Igwenyi IO, Tusubira D, Offor CE, Maduagwuna EK, Alum EU, Uti DE, Njoku A, Atoki VA, Awuchi CG. Aja PM, et al. Among authors: agu pc. Food Sci Nutr. 2023 Feb 18;11(6):2642-2653. doi: 10.1002/fsn3.3271. eCollection 2023 Jun. Food Sci Nutr. 2023. PMID: 37324904 Free PMC article.
In silico pharmacokinetic and therapeutic evaluation of Musa acuminata peels against aluminium chloride-induced hepatotoxicity in adult BALB/c mice.
Onohuean H, Onohuean EF, Igbinoba S, Odoma S, Usman I, Ifie JE, Alagbonsi AI, Moyosore AA, Udom GJ, Agu PC, Aja PM, Ezeonwumelu JOC, Al-Kuraishy HM, Batiha GE, Osuntoki AA. Onohuean H, et al. Among authors: agu pc. In Silico Pharmacol. 2024 May 23;12(1):46. doi: 10.1007/s40203-024-00216-1. eCollection 2024. In Silico Pharmacol. 2024. PMID: 38800619
Cucumeropsis mannii seed oil (CMSO) restores testicular mitochondrial dysfunctions by modulating the activities of dysregulated testicular mitochondrial enzymes in male albino rats exposed to bisphenol A.
Ogwoni HA, Aja PM, Eze ED, Agu PC, Moyosore AA, Ale BA, Ekpono EU, Awoke JN, Ogbu PN, Ukachi OU, Orji OU, Nweke PC, Egwu CO, Ekpono EU, Ewa GO, Igwenyi IO, Alum EU, Chukwu DC, Aja L, Ani GO, Offor CE, Yakubu OE, Maduagwuna E, Akobi JB, Noreen S, Awuchi CG. Ogwoni HA, et al. Among authors: agu pc. Food Sci Nutr. 2024 Aug 13;12(10):7854-7863. doi: 10.1002/fsn3.4379. eCollection 2024 Oct. Food Sci Nutr. 2024. PMID: 39479659 Free PMC article.
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