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Page 1
Prime-Pull Immunization of Mice with a BcfA-Adjuvanted Vaccine Elicits Sustained Mucosal Immunity That Prevents SARS-CoV-2 Infection and Pathology.
Shamseldin MM, Kenney A, Zani A, Evans JP, Zeng C, Read KA, Hall JM, Chaiwatpongsakorn S, Mahesh KC, Lu M, Eltobgy M, Denz P, Deora R, Li J, Peeples ME, Oestreich KJ, Liu SL, Corps KN, Yount JS, Dubey P. Shamseldin MM, et al. Among authors: eltobgy m. J Immunol. 2023 May 1;210(9):1257-1271. doi: 10.4049/jimmunol.2200297. J Immunol. 2023. PMID: 36881867 Free PMC article.
Caspase-11 regulates lung inflammation in response to house dust mites.
Abu Khweek A, Joldrichsen MR, Kim E, Attia Z, Krause K, Daily K, Estfanous S, Hamilton K, Badr A, Anne MNK, Eltobgy M, Corps KN, Carafice C, Zhang X, Gavrilin MA, Boyaka PN, Amer AO. Abu Khweek A, et al. Among authors: eltobgy m. Cell Immunol. 2021 Dec;370:104425. doi: 10.1016/j.cellimm.2021.104425. Epub 2021 Aug 29. Cell Immunol. 2021. PMID: 34800762 Free PMC article.
Caspase-4/11 exacerbates disease severity in SARS-CoV-2 infection by promoting inflammation and immunothrombosis.
Eltobgy MM, Zani A, Kenney AD, Estfanous S, Kim E, Badr A, Carafice C, Daily K, Whitham O, Pietrzak M, Webb A, Kawahara J, Eddy AC, Denz P, Lu M, Kc M, Peeples ME, Li J, Zhu J, Que J, Robinson R, Rosas Mejia O, Rayner RE, Hall-Stoodley L, Seveau S, Gavrilin MA, Zhang X, Thomas J, Kohlmeier JE, Suthar MS, Oltz E, Tedeschi A, Robledo-Avila FH, Partida-Sanchez S, Hemann EA, Abdelrazik E, Forero A, Nimjee SM, Boyaka PN, Cormet-Boyaka E, Yount JS, Amer AO. Eltobgy MM, et al. Proc Natl Acad Sci U S A. 2022 May 24;119(21):e2202012119. doi: 10.1073/pnas.2202012119. Epub 2022 May 19. Proc Natl Acad Sci U S A. 2022. PMID: 35588457 Free PMC article.
A next-generation intranasal trivalent MMS vaccine induces durable and broad protection against SARS-CoV-2 variants of concern.
Xu J, Zhang Y, Qu P, Shamseldin MM, Yoo SJ, Misny J, Thongpan I, Kc M, Hall JM, Evans JP, Eltobgy M, Lu M, Ye C, Chamblee M, Liang X, Martinez-Sobrido L, Amer AO, Yount JS, Boyaka PN, Peeples ME, Liu SL, Dubey P, Li J. Xu J, et al. Among authors: eltobgy m. Proc Natl Acad Sci U S A. 2023 Oct 10;120(41):e2220403120. doi: 10.1073/pnas.2220403120. Epub 2023 Oct 5. Proc Natl Acad Sci U S A. 2023. PMID: 37796985 Free PMC article.
Caspase-11 Mediates Neutrophil Chemotaxis and Extracellular Trap Formation During Acute Gouty Arthritis Through Alteration of Cofilin Phosphorylation.
Caution K, Young N, Robledo-Avila F, Krause K, Abu Khweek A, Hamilton K, Badr A, Vaidya A, Daily K, Gosu H, Anne MNK, Eltobgy M, Dakhlallah D, Argwal S, Estfanous S, Zhang X, Partida-Sanchez S, Gavrilin MA, Jarjour WN, Amer AO. Caution K, et al. Among authors: eltobgy m. Front Immunol. 2019 Nov 15;10:2519. doi: 10.3389/fimmu.2019.02519. eCollection 2019. Front Immunol. 2019. PMID: 31803174 Free PMC article.
Elevated Expression of MiR-17 in Microglia of Alzheimer's Disease Patients Abrogates Autophagy-Mediated Amyloid-β Degradation.
Estfanous S, Daily KP, Eltobgy M, Deems NP, Anne MNK, Krause K, Badr A, Hamilton K, Carafice C, Hegazi A, Abu Khweek A, Kelani H, Nimjee S, Awad H, Zhang X, Cormet-Boyaka E, Haffez H, Soror S, Mikhail A, Nuovo G, Barrientos RM, Gavrilin MA, Amer AO. Estfanous S, et al. Among authors: eltobgy m. Front Immunol. 2021 Jul 27;12:705581. doi: 10.3389/fimmu.2021.705581. eCollection 2021. Front Immunol. 2021. PMID: 34426734 Free PMC article.
Author Correction: Gasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo.
Estfanous S, Krause K, Anne MNK, Eltobgy M, Caution K, Khweek AA, Hamilton K, Badr A, Daily K, Carafice C, Baetzhold D, Zhang X, Li T, Wen H, Gavrilin MA, Haffez H, Soror S, Amer AO. Estfanous S, et al. Among authors: eltobgy m. Sci Rep. 2021 Jun 8;11(1):12447. doi: 10.1038/s41598-021-92047-9. Sci Rep. 2021. PMID: 34103646 Free PMC article. No abstract available.
DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates inflammation and amyloid-β deposition in Alzheimer's disease.
Daily KP, Badr A, Eltobgy M, Estfanous S, Whitham O, Tan MH, Carafice C, Krause K, McNamara A, Hamilton K, Houle S, Gupta S, Gupta GA, Madhu S, Fitzgerald J, Saadey AA, Laster B, Yan P, Webb A, Zhang X, Pietrzak M, Kokiko-Cochran ON, Ghoneim HE, Amer AO. Daily KP, et al. Among authors: eltobgy m. Alzheimers Res Ther. 2024 Feb 8;16(1):29. doi: 10.1186/s13195-024-01390-2. Alzheimers Res Ther. 2024. PMID: 38326859 Free PMC article.
CFTR Modulators Restore Acidification of Autophago-Lysosomes and Bacterial Clearance in Cystic Fibrosis Macrophages.
Badr A, Eltobgy M, Krause K, Hamilton K, Estfanous S, Daily KP, Abu Khweek A, Hegazi A, Anne MNK, Carafice C, Robledo-Avila F, Saqr Y, Zhang X, Bonfield TL, Gavrilin MA, Partida-Sanchez S, Seveau S, Cormet-Boyaka E, Amer AO. Badr A, et al. Among authors: eltobgy m. Front Cell Infect Microbiol. 2022 Feb 16;12:819554. doi: 10.3389/fcimb.2022.819554. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 35252032 Free PMC article.
36 results