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238 results

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Page 1
Choroid plexus-targeted NKCC1 overexpression to treat post-hemorrhagic hydrocephalus.
Sadegh C, Xu H, Sutin J, Fatou B, Gupta S, Pragana A, Taylor M, Kalugin PN, Zawadzki ME, Alturkistani O, Shipley FB, Dani N, Fame RM, Wurie Z, Talati P, Schleicher RL, Klein EM, Zhang Y, Holtzman MJ, Moore CI, Lin PY, Patel AB, Warf BC, Kimberly WT, Steen H, Andermann ML, Lehtinen MK. Sadegh C, et al. Among authors: holtzman mj. Neuron. 2023 May 17;111(10):1591-1608.e4. doi: 10.1016/j.neuron.2023.02.020. Epub 2023 Mar 8. Neuron. 2023. PMID: 36893755 Free PMC article.
A potent MAPK13-14 inhibitor prevents airway inflammation and mucus production.
Keeler SP, Wu K, Zhang Y, Mao D, Li M, Iberg CA, Austin SR, Glaser SA, Yantis J, Podgorny S, Brody SL, Chartock JR, Han Z, Byers DE, Romero AG, Holtzman MJ. Keeler SP, et al. Among authors: holtzman mj. Am J Physiol Lung Cell Mol Physiol. 2023 Dec 1;325(6):L726-L740. doi: 10.1152/ajplung.00183.2023. Epub 2023 Oct 17. Am J Physiol Lung Cell Mol Physiol. 2023. PMID: 37847710 Free PMC article.
IL-33 potentiates histaminergic itch.
Trier AM, Ver Heul AM, Fredman A, Le V, Wang Z, Auyeung K, Meixiong J, Lovato P, Holtzman MJ, Wang F, Dong X, Ji AL, Kim BS. Trier AM, et al. Among authors: holtzman mj. J Allergy Clin Immunol. 2024 Mar;153(3):852-859.e3. doi: 10.1016/j.jaci.2023.08.038. Epub 2023 Nov 18. J Allergy Clin Immunol. 2024. PMID: 37984799 Free article.
Divergent sensory pathways of sneezing and coughing.
Jiang H, Cui H, Chen M, Li F, Shen X, Guo CJ, Hoekel GE, Zhu Y, Han L, Wu K, Holtzman MJ, Liu Q. Jiang H, et al. Among authors: holtzman mj. Cell. 2024 Oct 17;187(21):5981-5997.e14. doi: 10.1016/j.cell.2024.08.009. Epub 2024 Sep 6. Cell. 2024. PMID: 39243765 Free PMC article.
A first-in-kind MAPK13 inhibitor that can correct stem cell reprogramming and post-injury disease.
Zhang Y, Wu K, Mao D, Iberg CA, Yin-Declue H, Sun K, Wikfors HA, Keeler SP, Li M, Young D, Yantis J, Crouch EC, Chartock JR, Han Z, Byers DE, Brody SL, Romero AG, Holtzman MJ. Zhang Y, et al. Among authors: holtzman mj. bioRxiv [Preprint]. 2024 Aug 22:2024.08.21.608990. doi: 10.1101/2024.08.21.608990. bioRxiv. 2024. PMID: 39229202 Free PMC article. Preprint.
MAPK13 controls structural remodeling and disease after epithelial injury.
Wu K, Zhang Y, Mao D, Iberg CA, Yin-Declue H, Sun K, Keeler SP, Wikfors HA, Young D, Yantis J, Austin SR, Byers DE, Brody SL, Crouch EC, Romero AG, Holtzman MJ. Wu K, et al. Among authors: holtzman mj. bioRxiv [Preprint]. 2024 Aug 10:2024.05.31.596863. doi: 10.1101/2024.05.31.596863. bioRxiv. 2024. PMID: 38895360 Free PMC article. Preprint.
238 results