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The NLRP3 inflammasome as a target for sensorineural hearing loss.
Gregory GE, Munro KJ, Couper KN, Pathmanaban ON, Brough D. Gregory GE, et al. Among authors: brough d. Clin Immunol. 2023 Apr;249:109287. doi: 10.1016/j.clim.2023.109287. Epub 2023 Mar 11. Clin Immunol. 2023. PMID: 36907540 Free article. Review.
Targeting the IL33-NLRP3 axis improves therapy for experimental cerebral malaria.
Strangward P, Haley MJ, Albornoz MG, Barrington J, Shaw T, Dookie R, Zeef L, Baker SM, Winter E, Tzeng TC, Golenbock DT, Cruickshank SM, Allan SM, Craig A, Liew FY, Brough D, Couper KN. Strangward P, et al. Among authors: brough d. Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):7404-7409. doi: 10.1073/pnas.1801737115. Epub 2018 Jun 28. Proc Natl Acad Sci U S A. 2018. PMID: 29954866 Free PMC article.
The inflammatory microenvironment in vestibular schwannoma.
Hannan CJ, Lewis D, O'Leary C, Donofrio CA, Evans DG, Roncaroli F, Brough D, King AT, Coope D, Pathmanaban ON. Hannan CJ, et al. Among authors: brough d. Neurooncol Adv. 2020 Feb 27;2(1):vdaa023. doi: 10.1093/noajnl/vdaa023. eCollection 2020 Jan-Dec. Neurooncol Adv. 2020. PMID: 32642684 Free PMC article. Review.
Anakinra in COVID-19: important considerations for clinical trials.
King A, Vail A, O'Leary C, Hannan C, Brough D, Patel H, Galea J, Ogungbenro K, Wright M, Pathmanaban O, Hulme S, Allan S. King A, et al. Among authors: brough d. Lancet Rheumatol. 2020 Jul;2(7):e379-e381. doi: 10.1016/S2665-9913(20)30160-0. Epub 2020 May 21. Lancet Rheumatol. 2020. PMID: 32835233 Free PMC article. No abstract available.
Inhibition of the NLRP3 inflammasome by HSP90 inhibitors.
Nizami S, Arunasalam K, Green J, Cook J, Lawrence CB, Zarganes-Tzitzikas T, Davis JB, Di Daniel E, Brough D. Nizami S, et al. Among authors: brough d. Immunology. 2021 Jan;162(1):84-91. doi: 10.1111/imm.13267. Epub 2020 Oct 30. Immunology. 2021. PMID: 32954500 Free PMC article.
The NLRP3-inflammasome as a sensor of organelle dysfunction.
Seoane PI, Lee B, Hoyle C, Yu S, Lopez-Castejon G, Lowe M, Brough D. Seoane PI, et al. Among authors: brough d. J Cell Biol. 2020 Dec 7;219(12):e202006194. doi: 10.1083/jcb.202006194. J Cell Biol. 2020. PMID: 33044555 Free PMC article. Review.
234 results