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AMPK activation by metformin protects against pulmonary hypertension in rats and relaxes isolated human pulmonary artery.
Abdelazeem H, Tu L, Thuillet R, Ottaviani M, Boulfrad A, Beck T, Senbel A, Mani S, Castier Y, Guyard A, Tran-Dinh A, El-Benna J, Longrois D, Silverstein AM, Guignabert C, Norel X. Abdelazeem H, et al. Among authors: senbel a. Eur J Pharmacol. 2023 May 5;946:175579. doi: 10.1016/j.ejphar.2023.175579. Epub 2023 Mar 11. Eur J Pharmacol. 2023. PMID: 36914083
In search of pulmonary hypertension treatments: Effect of 17β-estradiol on PGI2 pathway in human pulmonary artery.
Amgoud Y, Senbel A, Bouhadoun A, Abdelazeem H, Ozen G, Savané I, Manikpurage HD, Mani S, Tran-Dinh A, Castier Y, Guyard A, Longrois D, Silverstein AM, Norel X. Amgoud Y, et al. Among authors: senbel a. Prostaglandins Leukot Essent Fatty Acids. 2021 Sep;172:102321. doi: 10.1016/j.plefa.2021.102321. Epub 2021 Aug 9. Prostaglandins Leukot Essent Fatty Acids. 2021. PMID: 34403986
Ex vivo relaxations of pulmonary arteries induced by prostacyclin mimetics are highly dependent of the precontractile agents.
Benyahia C, Ozen G, Orie N, Ledwozyw A, Louedec L, Li F, Senbel AM, Silverstein A, Danel C, Longrois D, Clapp LH, Norel X, Topal G. Benyahia C, et al. Among authors: senbel am. Prostaglandins Other Lipid Mediat. 2015 Sep;121(Pt A):46-52. doi: 10.1016/j.prostaglandins.2015.09.002. Epub 2015 Sep 8. Prostaglandins Other Lipid Mediat. 2015. PMID: 26362969
International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E2 Receptors (EP1-4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions.
Norel X, Sugimoto Y, Ozen G, Abdelazeem H, Amgoud Y, Bouhadoun A, Bassiouni W, Goepp M, Mani S, Manikpurage HD, Senbel A, Longrois D, Heinemann A, Yao C, Clapp LH. Norel X, et al. Among authors: senbel a. Pharmacol Rev. 2020 Oct;72(4):910-968. doi: 10.1124/pr.120.019331. Pharmacol Rev. 2020. PMID: 32962984 Free PMC article.
47 results