Holtzman DM - Search Results

1

Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angiopathy.

Xiong M, Wang C, Gratuze M, Saadi F, Bao X, Bosch ME, Lee C, Jiang H, Serrano JR, Gonzales ER, Kipnis M, Holtzman DM. Xiong M, et al. Among authors: holtzman dm. Mol Neurodegener. 2023 Mar 16;18(1):17. doi: 10.1186/s13024-023-00610-x. Mol Neurodegener. 2023. PMID: 36922879 Free PMC article.

2

High density lipoprotein decreases beta-amyloid toxicity in cortical cell culture.

Farhangrazi ZS, Ying H, Bu G, Dugan LL, Fagan AM, Choi DW, Holtzman DM. Farhangrazi ZS, et al. Among authors: holtzman dm. Neuroreport. 1997 Mar 24;8(5):1127-30. doi: 10.1097/00001756-199703240-00013. Neuroreport. 1997. PMID: 9175098

3

Apolipoprotein E facilitates neuritic and cerebrovascular plaque formation in an Alzheimer's disease model.

Holtzman DM, Fagan AM, Mackey B, Tenkova T, Sartorius L, Paul SM, Bales K, Ashe KH, Irizarry MC, Hyman BT. Holtzman DM, et al. Ann Neurol. 2000 Jun;47(6):739-47. Ann Neurol. 2000. PMID: 10852539

4

Role of apoe/Abeta interactions in the pathogenesis of Alzheimer's disease and cerebral amyloid angiopathy.

Holtzman DM. Holtzman DM. J Mol Neurosci. 2001 Oct;17(2):147-55. doi: 10.1385/JMN:17:2:147. J Mol Neurosci. 2001. PMID: 11816788 Review.

5

Brain to plasma amyloid-beta efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease.

DeMattos RB, Bales KR, Cummins DJ, Paul SM, Holtzman DM. DeMattos RB, et al. Among authors: holtzman dm. Science. 2002 Mar 22;295(5563):2264-7. doi: 10.1126/science.1067568. Science. 2002. PMID: 11910111

6

Apolipoprotein E markedly facilitates age-dependent cerebral amyloid angiopathy and spontaneous hemorrhage in amyloid precursor protein transgenic mice.

Fryer JD, Taylor JW, DeMattos RB, Bales KR, Paul SM, Parsadanian M, Holtzman DM. Fryer JD, et al. Among authors: holtzman dm. J Neurosci. 2003 Aug 27;23(21):7889-96. doi: 10.1523/JNEUROSCI.23-21-07889.2003. J Neurosci. 2003. PMID: 12944519 Free PMC article.

7

Matrix metalloproteinase-9 and spontaneous hemorrhage in an animal model of cerebral amyloid angiopathy.

Lee JM, Yin KJ, Hsin I, Chen S, Fryer JD, Holtzman DM, Hsu CY, Xu J. Lee JM, et al. Among authors: holtzman dm. Ann Neurol. 2003 Sep;54(3):379-82. doi: 10.1002/ana.10671. Ann Neurol. 2003. PMID: 12953271

8

In vivo effects of ApoE and clusterin on amyloid-beta metabolism and neuropathology.

Holtzman DM. Holtzman DM. J Mol Neurosci. 2004;23(3):247-54. doi: 10.1385/JMN:23:3:247. J Mol Neurosci. 2004. PMID: 15181253 Review.

9

ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE.

Wahrle SE, Jiang H, Parsadanian M, Legleiter J, Han X, Fryer JD, Kowalewski T, Holtzman DM. Wahrle SE, et al. Among authors: holtzman dm. J Biol Chem. 2004 Sep 24;279(39):40987-93. doi: 10.1074/jbc.M407963200. Epub 2004 Jul 21. J Biol Chem. 2004. PMID: 15269217 Free article.

10

ApoAI deficiency results in marked reductions in plasma cholesterol but no alterations in amyloid-beta pathology in a mouse model of Alzheimer's disease-like cerebral amyloidosis.

Fagan AM, Christopher E, Taylor JW, Parsadanian M, Spinner M, Watson M, Fryer JD, Wahrle S, Bales KR, Paul SM, Holtzman DM. Fagan AM, et al. Among authors: holtzman dm. Am J Pathol. 2004 Oct;165(4):1413-22. doi: 10.1016/s0002-9440(10)63399-8. Am J Pathol. 2004. PMID: 15466405 Free PMC article.

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