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Page 1
Targeted regulation of transcription in primary cells using CRISPRa and CRISPRi.
Jensen TI, Mikkelsen NS, Gao Z, Foßelteder J, Pabst G, Axelgaard E, Laustsen A, König S, Reinisch A, Bak RO. Jensen TI, et al. Among authors: mikkelsen ns. Genome Res. 2021 Nov;31(11):2120-2130. doi: 10.1101/gr.275607.121. Epub 2021 Aug 18. Genome Res. 2021. PMID: 34407984 Free PMC article.
A truncated reverse transcriptase enhances prime editing by split AAV vectors.
Gao Z, Ravendran S, Mikkelsen NS, Haldrup J, Cai H, Ding X, Paludan SR, Thomsen MK, Mikkelsen JG, Bak RO. Gao Z, et al. Among authors: mikkelsen ns. Mol Ther. 2022 Sep 7;30(9):2942-2951. doi: 10.1016/j.ymthe.2022.07.001. Epub 2022 Jul 8. Mol Ther. 2022. PMID: 35808824 Free PMC article.
Enrichment strategies to enhance genome editing.
Mikkelsen NS, Bak RO. Mikkelsen NS, et al. J Biomed Sci. 2023 Jul 1;30(1):51. doi: 10.1186/s12929-023-00943-1. J Biomed Sci. 2023. PMID: 37393268 Free PMC article. Review.
CRISPR activation to characterize splice-altering variants in easily accessible cells.
Terkelsen T, Mikkelsen NS, Bak EN, Vad-Nielsen J, Blechingberg J, Weiss S, Drue SO, Andersen H, Andresen BS, Bak RO, Jensen UB. Terkelsen T, et al. Among authors: mikkelsen ns. Am J Hum Genet. 2024 Feb 1;111(2):309-322. doi: 10.1016/j.ajhg.2023.12.024. Epub 2024 Jan 24. Am J Hum Genet. 2024. PMID: 38272032 Free PMC article.