Fluiter K - Search Results

1

The systemic inhibition of the terminal complement system reduces neuroinflammation but does not improve motor function in mouse models of CMT1A with overexpressed PMP22.

Michailidou I, Vreijling J, Rumpf M, Loos M, Koopmans B, Vlek N, Straat N, Agaser C, Kuipers TB, Mei H, Baas F, Fluiter K. Michailidou I, et al. Among authors: fluiter k. Curr Res Neurobiol. 2023 Feb 4;4:100077. doi: 10.1016/j.crneur.2023.100077. eCollection 2023. Curr Res Neurobiol. 2023. PMID: 36926597 Free PMC article.

2

Tumor genotype-specific growth inhibition in vivo by antisense oligonucleotides against a polymorphic site of the large subunit of human RNA polymerase II.

Fluiter K, ten Asbroek AL, van Groenigen M, Nooij M, Aalders MC, Baas F. Fluiter K, et al. Cancer Res. 2002 Apr 1;62(7):2024-8. Cancer Res. 2002. PMID: 11929820

3

Evaluation of LNA-modified DNAzymes targeting a single nucleotide polymorphism in the large subunit of RNA polymerase II.

Fluiter K, Frieden M, Vreijling J, Koch T, Baas F. Fluiter K, et al. Oligonucleotides. 2005 Dec;15(4):246-54. doi: 10.1089/oli.2005.15.246. Oligonucleotides. 2005. PMID: 16396619

4

Evaluation of locked nucleic acid-modified small interfering RNA in vitro and in vivo.

Mook OR, Baas F, de Wissel MB, Fluiter K. Mook OR, et al. Among authors: fluiter k. Mol Cancer Ther. 2007 Mar;6(3):833-43. doi: 10.1158/1535-7163.MCT-06-0195. Mol Cancer Ther. 2007. PMID: 17363479 Free article.

5

The therapeutic potential of LNA-modified siRNAs: reduction of off-target effects by chemical modification of the siRNA sequence.

Fluiter K, Mook OR, Baas F. Fluiter K, et al. Methods Mol Biol. 2009;487:189-203. doi: 10.1007/978-1-60327-547-7_9. Methods Mol Biol. 2009. PMID: 19301648 Review.

6

Filling the gap in LNA antisense oligo gapmers: the effects of unlocked nucleic acid (UNA) and 4'-C-hydroxymethyl-DNA modifications on RNase H recruitment and efficacy of an LNA gapmer.

Fluiter K, Mook OR, Vreijling J, Langkjaer N, Højland T, Wengel J, Baas F. Fluiter K, et al. Mol Biosyst. 2009 Aug;5(8):838-43. doi: 10.1039/b903922h. Epub 2009 May 19. Mol Biosyst. 2009. PMID: 19603119

7

In vivo efficacy and off-target effects of locked nucleic acid (LNA) and unlocked nucleic acid (UNA) modified siRNA and small internally segmented interfering RNA (sisiRNA) in mice bearing human tumor xenografts.

Mook O, Vreijling J, Wengel SL, Wengel J, Zhou C, Chattopadhyaya J, Baas F, Fluiter K. Mook O, et al. Among authors: fluiter k. Artif DNA PNA XNA. 2010 Jul;1(1):36-44. doi: 10.4161/adna.1.1.12204. Artif DNA PNA XNA. 2010. PMID: 21687525 Free PMC article.

8

A frameshift mutation in LRSAM1 is responsible for a dominant hereditary polyneuropathy.

Weterman MA, Sorrentino V, Kasher PR, Jakobs ME, van Engelen BG, Fluiter K, de Wissel MB, Sizarov A, Nürnberg G, Nürnberg P, Zelcer N, Schelhaas HJ, Baas F. Weterman MA, et al. Among authors: fluiter k. Hum Mol Genet. 2012 Jan 15;21(2):358-70. doi: 10.1093/hmg/ddr471. Epub 2011 Oct 19. Hum Mol Genet. 2012. PMID: 22012984 Free PMC article.

9

Inhibition of the membrane attack complex of the complement system reduces secondary neuroaxonal loss and promotes neurologic recovery after traumatic brain injury in mice.

Fluiter K, Opperhuizen AL, Morgan BP, Baas F, Ramaglia V. Fluiter K, et al. J Immunol. 2014 Mar 1;192(5):2339-48. doi: 10.4049/jimmunol.1302793. Epub 2014 Jan 31. J Immunol. 2014. PMID: 24489093

10

M. leprae components induce nerve damage by complement activation: identification of lipoarabinomannan as the dominant complement activator.

Bahia El Idrissi N, Das PK, Fluiter K, Rosa PS, Vreijling J, Troost D, Morgan BP, Baas F, Ramaglia V. Bahia El Idrissi N, et al. Among authors: fluiter k. Acta Neuropathol. 2015 May;129(5):653-67. doi: 10.1007/s00401-015-1404-5. Epub 2015 Mar 15. Acta Neuropathol. 2015. PMID: 25772973 Free PMC article.

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