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ANGPTL3 targeting: The power of versatile lipid-lowering.
Pessentheiner AR, Ramms B, Gordts PLSM. Pessentheiner AR, et al. Atherosclerosis. 2018 Jan;268:185-187. doi: 10.1016/j.atherosclerosis.2017.10.002. Epub 2017 Oct 6. Atherosclerosis. 2018. PMID: 29111225 Free PMC article. No abstract available.
ApoC-III ASO promotes tissue LPL activity in the absence of apoE-mediated TRL clearance.
Ramms B, Patel S, Nora C, Pessentheiner AR, Chang MW, Green CR, Golden GJ, Secrest P, Krauss RM, Metallo CM, Benner C, Alexander VJ, Witztum JL, Tsimikas S, Esko JD, Gordts PLSM. Ramms B, et al. Among authors: pessentheiner ar. J Lipid Res. 2019 Aug;60(8):1379-1395. doi: 10.1194/jlr.M093740. Epub 2019 May 14. J Lipid Res. 2019. PMID: 31092690 Free PMC article.
microRNA-483 ameliorates hypercholesterolemia by inhibiting PCSK9 production.
Dong J, He M, Li J, Pessentheiner A, Wang C, Zhang J, Sun Y, Wang WT, Zhang Y, Liu J, Wang SC, Huang PH, Gordts PL, Yuan ZY, Tsimikas S, Shyy JY. Dong J, et al. JCI Insight. 2020 Dec 3;5(23):e143812. doi: 10.1172/jci.insight.143812. JCI Insight. 2020. PMID: 33119548 Free PMC article.
Impaired mitophagy in Sanfilippo a mice causes hypertriglyceridemia and brown adipose tissue activation.
Tillo M, Lamanna WC, Dwyer CA, Sandoval DR, Pessentheiner AR, Al-Azzam N, Sarrazin S, Gonzales JC, Kan SH, Andreyev AY, Schultheis N, Thacker BE, Glass CA, Dickson PI, Wang RY, Selleck SB, Esko JD, Gordts PLSM. Tillo M, et al. Among authors: pessentheiner ar. J Biol Chem. 2022 Aug;298(8):102159. doi: 10.1016/j.jbc.2022.102159. Epub 2022 Jun 22. J Biol Chem. 2022. PMID: 35750212 Free PMC article.
Adipocyte SIRT1 knockout promotes PPARγ activity, adipogenesis and insulin sensitivity in chronic-HFD and obesity.
Mayoral R, Osborn O, McNelis J, Johnson AM, Oh DY, Izquierdo CL, Chung H, Li P, Traves PG, Bandyopadhyay G, Pessentheiner AR, Ofrecio JM, Cook JR, Qiang L, Accili D, Olefsky JM. Mayoral R, et al. Among authors: pessentheiner ar. Mol Metab. 2015 Mar 5;4(5):378-91. doi: 10.1016/j.molmet.2015.02.007. eCollection 2015 May. Mol Metab. 2015. PMID: 25973386 Free PMC article.
Loss of ABHD15 Impairs the Anti-lipolytic Action of Insulin by Altering PDE3B Stability and Contributes to Insulin Resistance.
Xia W, Pessentheiner AR, Hofer DC, Amor M, Schreiber R, Schoiswohl G, Eichmann TO, Walenta E, Itariu B, Prager G, Hackl H, Stulnig T, Kratky D, Rülicke T, Bogner-Strauss JG. Xia W, et al. Among authors: pessentheiner ar. Cell Rep. 2018 May 15;23(7):1948-1961. doi: 10.1016/j.celrep.2018.04.055. Cell Rep. 2018. PMID: 29768196 Free PMC article.
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