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11β-HSD1 inhibition does not affect murine tumour angiogenesis but may exert a selective effect on tumour growth by modulating inflammation and fibrosis.
Davidson CT, Miller E, Muir M, Dawson JC, Lee M, Aitken S, Serrels A, Webster SP, Homer NZM, Andrew R, Brunton VG, Hadoke PWF, Walker BR. Davidson CT, et al. Among authors: miller e. PLoS One. 2023 Mar 20;18(3):e0255709. doi: 10.1371/journal.pone.0255709. eCollection 2023. PLoS One. 2023. PMID: 36940215 Free PMC article.
Increased angiogenesis protects against adipose hypoxia and fibrosis in metabolic disease-resistant 11β-hydroxysteroid dehydrogenase type 1 (HSD1)-deficient mice.
Michailidou Z, Turban S, Miller E, Zou X, Schrader J, Ratcliffe PJ, Hadoke PW, Walker BR, Iredale JP, Morton NM, Seckl JR. Michailidou Z, et al. Among authors: miller e. J Biol Chem. 2012 Feb 3;287(6):4188-97. doi: 10.1074/jbc.M111.259325. Epub 2011 Dec 12. J Biol Chem. 2012. PMID: 22158867 Free PMC article.
11β-hydroxysteroid dehydrogenase type 1 deficiency in bone marrow-derived cells reduces atherosclerosis.
Kipari T, Hadoke PW, Iqbal J, Man TY, Miller E, Coutinho AE, Zhang Z, Sullivan KM, Mitic T, Livingstone DE, Schrecker C, Samuel K, White CI, Bouhlel MA, Chinetti-Gbaguidi G, Staels B, Andrew R, Walker BR, Savill JS, Chapman KE, Seckl JR. Kipari T, et al. Among authors: miller e. FASEB J. 2013 Apr;27(4):1519-31. doi: 10.1096/fj.12-219105. Epub 2013 Jan 9. FASEB J. 2013. PMID: 23303209 Free PMC article.
7,076 results