Vorobieva A - Search Results

1

Treponema pallidum subsp. pallidum with an Artificially impaired TprK antigenic variation system is attenuated in the Rabbit model of syphilis.

Romeis E, Lieberman NAP, Molini B, Tantalo LC, Chung B, Phung Q, Avendaño C, Vorobieva A, Greninger AL, Giacani L. Romeis E, et al. Among authors: vorobieva a. PLoS Pathog. 2023 Mar 20;19(3):e1011259. doi: 10.1371/journal.ppat.1011259. eCollection 2023 Mar. PLoS Pathog. 2023. PMID: 36940224 Free PMC article.

2

Balancing Specificity and Promiscuity in Enzyme Evolution: Multidimensional Activity Transitions in the Alkaline Phosphatase Superfamily.

van Loo B, Bayer CD, Fischer G, Jonas S, Valkov E, Mohamed MF, Vorobieva A, Dutruel C, Hyvönen M, Hollfelder F. van Loo B, et al. Among authors: vorobieva a. J Am Chem Soc. 2019 Jan 9;141(1):370-387. doi: 10.1021/jacs.8b10290. Epub 2018 Dec 20. J Am Chem Soc. 2019. PMID: 30497259

3

Improving the Efficiency of Ligand-Binding Protein Design with Molecular Dynamics Simulations.

Barros EP, Schiffer JM, Vorobieva A, Dou J, Baker D, Amaro RE. Barros EP, et al. Among authors: vorobieva a. J Chem Theory Comput. 2019 Oct 8;15(10):5703-5715. doi: 10.1021/acs.jctc.9b00483. Epub 2019 Sep 10. J Chem Theory Comput. 2019. PMID: 31442033 Free PMC article.

4

B-Cell Epitope Mapping of TprC and TprD Variants of Treponema pallidum Subspecies Informs Vaccine Development for Human Treponematoses.

Molini B, Fernandez MC, Godornes C, Vorobieva A, Lukehart SA, Giacani L. Molini B, et al. Among authors: vorobieva a. Front Immunol. 2022 Mar 29;13:862491. doi: 10.3389/fimmu.2022.862491. eCollection 2022. Front Immunol. 2022. PMID: 35422800 Free PMC article.

5

Rationale in Custom Design of Transmembrane β-Barrel Pores.

Vorobieva AA. Vorobieva AA. Methods Mol Biol. 2024;2778:345-366. doi: 10.1007/978-1-0716-3734-0_21. Methods Mol Biol. 2024. PMID: 38478288

6

Validation of de novo designed water-soluble and transmembrane β-barrels by in silico folding and melting.

Hermosilla AM, Berner C, Ovchinnikov S, Vorobieva AA. Hermosilla AM, et al. Among authors: vorobieva aa. Protein Sci. 2024 Jul;33(7):e5033. doi: 10.1002/pro.5033. Protein Sci. 2024. PMID: 38864690

7

Design and optimization of enzymatic activity in a de novo β-barrel scaffold.

Kipnis Y, Chaib AO, Vorobieva AA, Cai G, Reggiano G, Basanta B, Kumar E, Mittl PRE, Hilvert D, Baker D. Kipnis Y, et al. Among authors: vorobieva aa. Protein Sci. 2022 Nov;31(11):e4405. doi: 10.1002/pro.4405. Protein Sci. 2022. PMID: 36305767 Free PMC article.

8

Evolutionary adaptation of the protein folding pathway for secretability.

Smets D, Tsirigotaki A, Smit JH, Krishnamurthy S, Portaliou AG, Vorobieva A, Vranken W, Karamanou S, Economou A. Smets D, et al. Among authors: vorobieva a. EMBO J. 2022 Dec 1;41(23):e111344. doi: 10.15252/embj.2022111344. Epub 2022 Aug 29. EMBO J. 2022. PMID: 36031863 Free PMC article.

9

Principles and Methods in Computational Membrane Protein Design.

Vorobieva AA. Vorobieva AA. J Mol Biol. 2021 Oct 1;433(20):167154. doi: 10.1016/j.jmb.2021.167154. Epub 2021 Jul 14. J Mol Biol. 2021. PMID: 34271008 Review.

10

De novo design of a fluorescence-activating β-barrel.

Dou J, Vorobieva AA, Sheffler W, Doyle LA, Park H, Bick MJ, Mao B, Foight GW, Lee MY, Gagnon LA, Carter L, Sankaran B, Ovchinnikov S, Marcos E, Huang PS, Vaughan JC, Stoddard BL, Baker D. Dou J, et al. Among authors: vorobieva aa. Nature. 2018 Sep;561(7724):485-491. doi: 10.1038/s41586-018-0509-0. Epub 2018 Sep 12. Nature. 2018. PMID: 30209393 Free PMC article.

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