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Cancer vaccines based on whole-tumor lysate or neoepitopes with validated HLA binding outperform those with predicted HLA-binding affinity.
Fritah H, Graciotti M, Lai-Lai Chiang C, Huguenin-Bergenat AL, Petremand R, Ahmed R, Guillaume P, Schmidt J, Stevenson BJ, Gfeller D, Harari A, Kandalaft LE. Fritah H, et al. Among authors: gfeller d. iScience. 2023 Feb 27;26(4):106288. doi: 10.1016/j.isci.2023.106288. eCollection 2023 Apr 21. iScience. 2023. PMID: 36950115 Free PMC article.
Allosteric Modulation of Binding Specificity by Alternative Packing of Protein Cores.
Ben-David M, Huang H, Sun MGF, Corbi-Verge C, Petsalaki E, Liu K, Gfeller D, Garg P, Tempel W, Sochirca I, Shifman JM, Davidson A, Min J, Kim PM, Sidhu SS. Ben-David M, et al. Among authors: gfeller d. J Mol Biol. 2019 Jan 18;431(2):336-350. doi: 10.1016/j.jmb.2018.11.018. Epub 2018 Nov 22. J Mol Biol. 2019. PMID: 30471255
SH3 interactome conserves general function over specific form.
Xin X, Gfeller D, Cheng J, Tonikian R, Sun L, Guo A, Lopez L, Pavlenco A, Akintobi A, Zhang Y, Rual JF, Currell B, Seshagiri S, Hao T, Yang X, Shen YA, Salehi-Ashtiani K, Li J, Cheng AT, Bouamalay D, Lugari A, Hill DE, Grimes ML, Drubin DG, Grant BD, Vidal M, Boone C, Sidhu SS, Bader GD. Xin X, et al. Among authors: gfeller d. Mol Syst Biol. 2013;9:652. doi: 10.1038/msb.2013.9. Mol Syst Biol. 2013. PMID: 23549480 Free PMC article.
Sequence determinants of a microtubule tip localization signal (MtLS).
Buey RM, Sen I, Kortt O, Mohan R, Gfeller D, Veprintsev D, Kretzschmar I, Scheuermann J, Neri D, Zoete V, Michielin O, de Pereda JM, Akhmanova A, Volkmer R, Steinmetz MO. Buey RM, et al. Among authors: gfeller d. J Biol Chem. 2012 Aug 17;287(34):28227-42. doi: 10.1074/jbc.M112.373928. Epub 2012 Jun 13. J Biol Chem. 2012. PMID: 22696216 Free PMC article.
The multiple-specificity landscape of modular peptide recognition domains.
Gfeller D, Butty F, Wierzbicka M, Verschueren E, Vanhee P, Huang H, Ernst A, Dar N, Stagljar I, Serrano L, Sidhu SS, Bader GD, Kim PM. Gfeller D, et al. Mol Syst Biol. 2011 Apr 26;7:484. doi: 10.1038/msb.2011.18. Mol Syst Biol. 2011. PMID: 21525870 Free PMC article.
Current tools for predicting cancer-specific T cell immunity.
Gfeller D, Bassani-Sternberg M, Schmidt J, Luescher IF. Gfeller D, et al. Oncoimmunology. 2016 Apr 25;5(7):e1177691. doi: 10.1080/2162402X.2016.1177691. eCollection 2016 Jul. Oncoimmunology. 2016. PMID: 27622028 Free PMC article. Review.
Sensitive and frequent identification of high avidity neo-epitope specific CD8 + T cells in immunotherapy-naive ovarian cancer.
Bobisse S, Genolet R, Roberti A, Tanyi JL, Racle J, Stevenson BJ, Iseli C, Michel A, Le Bitoux MA, Guillaume P, Schmidt J, Bianchi V, Dangaj D, Fenwick C, Derré L, Xenarios I, Michielin O, Romero P, Monos DS, Zoete V, Gfeller D, Kandalaft LE, Coukos G, Harari A. Bobisse S, et al. Among authors: gfeller d. Nat Commun. 2018 Mar 15;9(1):1092. doi: 10.1038/s41467-018-03301-0. Nat Commun. 2018. PMID: 29545564 Free PMC article.
87 results