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Ultra-low volume intradermal administration of radiation-attenuated sporozoites with the glycolipid adjuvant 7DW8-5 completely protects mice against malaria.
Watson FN, Shears MJ, Kalata AC, Duncombe CJ, Seilie AM, Chavtur C, Conrad E, Cruz Talavera I, Raappana A, Sather DN, Chakravarty S, Sim BKL, Hoffman SL, Tsuji M, Murphy SC. Watson FN, et al. Among authors: cruz talavera i. Sci Rep. 2024 Feb 4;14(1):2881. doi: 10.1038/s41598-024-53118-9. Sci Rep. 2024. PMID: 38311678 Free PMC article.
More time to kill: A longer liver stage increases T cell-mediated protection against pre-erythrocytic malaria.
Yadav N, Parthiban C, Billman ZP, Stone BC, Watson FN, Zhou K, Olsen TM, Cruz Talavera I, Seilie AM, Kalata AC, Matsubara J, Shears MJ, Reynolds RA, Murphy SC. Yadav N, et al. Among authors: cruz talavera i. iScience. 2023 Nov 20;26(12):108489. doi: 10.1016/j.isci.2023.108489. eCollection 2023 Dec 15. iScience. 2023. PMID: 38162031 Free PMC article.
Memory T cells possess an innate-like function in local protection from mucosal infection.
Arkatkar T, Davé V, Cruz Talavera I, Graham JB, Swarts JL, Hughes SM, Bell TA, Hock P, Farrington J, Shaw GD, Kirby A, Fialkow M, Huang ML, Jerome KR, Ferris MT, Hladik F, Schiffer JT, Prlic M, Lund JM. Arkatkar T, et al. Among authors: cruz talavera i. J Clin Invest. 2023 May 15;133(10):e162800. doi: 10.1172/JCI162800. J Clin Invest. 2023. PMID: 36951943 Free PMC article.
Cryopreserved Sporozoites with and without the Glycolipid Adjuvant 7DW8-5 Protect in Prime-and-Trap Malaria Vaccination.
Watson FN, Shears MJ, Matsubara J, Kalata AC, Seilie AM, Cruz Talavera I, Olsen TM, Tsuji M, Chakravarty S, Sim BKL, Hoffman SL, Murphy SC. Watson FN, et al. Among authors: cruz talavera i. Am J Trop Med Hyg. 2022 Feb 28;106(4):1227-1236. doi: 10.4269/ajtmh.21-1084. Print 2022 Apr 6. Am J Trop Med Hyg. 2022. PMID: 35226868 Free PMC article.