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Page 1
Sedentary behavior in mice induces metabolic inflexibility by suppressing skeletal muscle pyruvate metabolism.
Siripoksup P, Cao G, Cluntun AA, Maschek JA, Pearce Q, Brothwell MJ, Jeong MY, Eshima H, Ferrara PJ, Opurum PC, Mahmassani ZS, Peterlin AD, Watanabe S, Walsh MA, Taylor EB, Cox JE, Drummond MJ, Rutter J, Funai K. Siripoksup P, et al. Among authors: pearce q. J Clin Invest. 2024 Apr 23;134(11):e167371. doi: 10.1172/JCI167371. J Clin Invest. 2024. PMID: 38652544 Free PMC article.
Direct mitochondrial import of lactate supports resilient carbohydrate oxidation.
Cluntun AA, Visker JR, Velasco-Silva JN, Lang MJ, Cedeño-Rosario L, Shankar TS, Hamouche R, Ling J, Kim JE, Toshniwal AG, Low HK, Cunningham CN, Carrington J, Catrow JL, Pearce Q, Jeong MY, Bott AJ, Narbona-Pérez ÁJ, Stanley CE, Li Q, Eberhardt DR, Morgan JT, Yadav T, Wells CE, Ramadurai DKA, Swiatek WI, Chaudhuri D, Rothstein JD, Muoio DM, Paulo JA, Gygi SP, Baker SA, Navankasattusas S, Cox JE, Funai K, Drakos SG, Rutter J, Ducker GS. Cluntun AA, et al. Among authors: pearce q. bioRxiv [Preprint]. 2024 Oct 8:2024.10.07.617073. doi: 10.1101/2024.10.07.617073. bioRxiv. 2024. PMID: 39416192 Free PMC article. Preprint.
Cardiolipin deficiency disrupts CoQ redox state and induces steatohepatitis.
Brothwell MJ, Cao 曹国燊 G, Maschek JA, Poss AM, Peterlin AD, Wang 汪立平 L, Baker TB, Shahtout JL, Siripoksup P, Pearce QJ, Johnson JM, Finger FM, Prola A, Pellizzari SA, Hale GL, Manuel AM, Watanabe 渡邉真也 S, Miranda ER, Affolter KE, Tippetts TS, Nikolova LS, Choi 崔蘭煕 RH, Decker ST, Patil M, Catrow JL, Holland WL, Nowinski SM, Lark DS, Fisher-Wellman KH, Mimche PN, Evason KJ, Cox JE, Summers SA, Gerhart-Hines Z, Funai 船井勝彦 K. Brothwell MJ, et al. Among authors: pearce qj. bioRxiv [Preprint]. 2024 Oct 10:2024.10.10.617517. doi: 10.1101/2024.10.10.617517. bioRxiv. 2024. PMID: 39416056 Free PMC article. Preprint.