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54 results

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Page 1
Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus MYNRL15.
Ng M, Verboon L, Issa H, Bhayadia R, Vermunt MW, Winkler R, Schüler L, Alejo O, Schuschel K, Regenyi E, Borchert D, Heuser M, Reinhardt D, Yaspo ML, Heckl D, Klusmann JH. Ng M, et al. Among authors: heckl d. iScience. 2023 Sep 7;26(10):107844. doi: 10.1016/j.isci.2023.107844. eCollection 2023 Oct 20. iScience. 2023. PMID: 37766974 Free PMC article.
Preclinical testing of miRNA-193b-3p mimic in acute myeloid leukemias.
Issa H, Bhayadia R, Winkler R, Swart LE, Heckl D, Klusmann JH. Issa H, et al. Among authors: heckl d. Leukemia. 2023 Jul;37(7):1583-1587. doi: 10.1038/s41375-023-01937-6. Epub 2023 Jun 13. Leukemia. 2023. PMID: 37311946 Free PMC article. No abstract available.
RUNX1 isoform disequilibrium promotes the development of trisomy 21-associated myeloid leukemia.
Gialesaki S, Bräuer-Hartmann D, Issa H, Bhayadia R, Alejo-Valle O, Verboon L, Schmell AL, Laszig S, Regényi E, Schuschel K, Labuhn M, Ng M, Winkler R, Ihling C, Sinz A, Glaß M, Hüttelmaier S, Matzk S, Schmid L, Strüwe FJ, Kadel SK, Reinhardt D, Yaspo ML, Heckl D, Klusmann JH. Gialesaki S, et al. Among authors: heckl d. Blood. 2023 Mar 9;141(10):1105-1118. doi: 10.1182/blood.2022017619. Blood. 2023. PMID: 36493345 Free PMC article.
Genetic barcoding systematically compares genes in del(5q) MDS and reveals a central role for CSNK1A1 in clonal expansion.
Stalmann USA, Ticconi F, Snoeren IAM, Li R, Gleitz HFE, Cowley GS, McConkey ME, Wong AB, Schmitz S, Fuchs SNR, Sood S, Leimkühler NB, Martinez-Høyer S, Banjanin B, Root D, Brümmendorf TH, Pearce JE, Schuppert A, Bindels EMJ, Essers MA, Heckl D, Stiehl T, Costa IG, Ebert BL, Schneider RK. Stalmann USA, et al. Among authors: heckl d. Blood Adv. 2022 Mar 22;6(6):1780-1796. doi: 10.1182/bloodadvances.2021006061. Blood Adv. 2022. PMID: 35016204 Free PMC article.
Correction: Effective drug treatment identified by in vivo screening in a transplantable patient-derived xenograft model of chronic myelomonocytic leukemia.
Kloos A, Mintzas K, Winckler L, Gabdoulline R, Alwie Y, Jyotsana N, Kattre N, Schottmann R, Scherr M, Gupta C, Adams FF, Schwarzer A, Heckl D, Schambach A, Imren S, Humphries RK, Ganser A, Thol F, Heuser M. Kloos A, et al. Among authors: heckl d. Leukemia. 2021 Dec;35(12):3629. doi: 10.1038/s41375-021-01459-z. Leukemia. 2021. PMID: 34728793 Free PMC article. No abstract available.
The megakaryocytic transcription factor ARID3A suppresses leukemia pathogenesis.
Alejo-Valle O, Weigert K, Bhayadia R, Ng M, Issa H, Beyer C, Emmrich S, Schuschel K, Ihling C, Sinz A, Zimmermann M, Wickenhauser C, Flasinski M, Regenyi E, Labuhn M, Reinhardt D, Yaspo ML, Heckl D, Klusmann JH. Alejo-Valle O, et al. Among authors: heckl d. Blood. 2022 Feb 3;139(5):651-665. doi: 10.1182/blood.2021012231. Blood. 2022. PMID: 34570885 Free PMC article.
54 results