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Page 1
Antibody-based delivery of interleukin-2 modulates the immunosuppressive tumor microenvironment and achieves cure in pancreatic ductal adenocarcinoma syngeneic mice.
Carbone C, De Luca R, Puca E, Agostini A, Caggiano A, Priori L, Esposito A, Ascrizzi S, Piro G, Salvatore L, De Sanctis F, Ugel S, Corbo V, Neri D, Tortora G. Carbone C, et al. Among authors: ascrizzi s. J Exp Clin Cancer Res. 2025 Jan 7;44(1):7. doi: 10.1186/s13046-024-03238-x. J Exp Clin Cancer Res. 2025. PMID: 39773310 Free PMC article.
Colorectal cancer patients-derived immunity-organoid platform unveils cancer-specific tissue markers associated with immunotherapy resistance.
Esposito A, Agostini A, Quero G, Piro G, Priori L, Caggiano A, Scaglione G, Battaglia A, Calegari MA, Salvatore L, Bensi M, Maratta MG, Ceccarelli A, Trovato G, Genovese G, Gurreri E, Ascrizzi S, Martini M, Fiorillo C, Fattorossi A, De Sanctis F, Ugel S, Corbo V, Alfieri S, Tortora G, Carbone C. Esposito A, et al. Among authors: ascrizzi s. Cell Death Dis. 2024 Dec 4;15(12):878. doi: 10.1038/s41419-024-07266-5. Cell Death Dis. 2024. PMID: 39632825 Free PMC article.
An unbiased lncRNA dropout CRISPR-Cas9 screen reveals RP11-350G8.5 as a novel therapeutic target for multiple myeloma.
Grillone K, Ascrizzi S, Cremaschi P, Amato J, Polerà N, Croci O, Rocca R, Riillo C, Conforti F, Graziano R, Brancaccio D, Caracciolo D, Alcaro S, Pagano B, Randazzo A, Tagliaferri P, Iorio F, Tassone P. Grillone K, et al. Among authors: ascrizzi s. Blood. 2024 Oct 17;144(16):1705-1721. doi: 10.1182/blood.2023021991. Blood. 2024. PMID: 39158066 Free PMC article.
LNA-i-miR-221 activity in colorectal cancer: A reverse translational investigation.
Ali A, Grillone K, Ascrizzi S, Caridà G, Fiorillo L, Ciliberto D, Staropoli N, Tagliaferri P, Tassone P, Di Martino MT. Ali A, et al. Among authors: ascrizzi s. Mol Ther Nucleic Acids. 2024 May 20;35(2):102221. doi: 10.1016/j.omtn.2024.102221. eCollection 2024 Jun 11. Mol Ther Nucleic Acids. 2024. PMID: 38868363 Free PMC article.
UMG1/CD3ε-bispecific T-cell engager redirects T-cell cytotoxicity against diffuse large B-cell lymphoma.
Caracciolo D, Polerà N, Belmonte B, Conforti F, Signorelli S, Gulino A, Staropoli N, Tuccillo FM, Bonelli P, Juli G, Grillone K, Ascrizzi S, Cirillo M, Migale L, Ballerini A, Pelizon C, Di Martino MT, Tagliaferri P, Riillo C, Tassone P. Caracciolo D, et al. Among authors: ascrizzi s. Br J Haematol. 2024 Feb;204(2):555-560. doi: 10.1111/bjh.19183. Epub 2023 Nov 14. Br J Haematol. 2024. PMID: 37963444
A Pronectin™ AXL-targeted first-in-class bispecific T cell engager (pAXLxCD3ε) for ovarian cancer.
Riillo C, Polerà N, Di Martino MT, Juli G, Hokanson CA, Odineca T, Signorelli S, Grillone K, Ascrizzi S, Mancuso A, Staropoli N, Caparello B, Cerra M, Nisticò G, Tagliaferri P, Crea R, Caracciolo D, Tassone P. Riillo C, et al. Among authors: ascrizzi s. J Transl Med. 2023 May 4;21(1):301. doi: 10.1186/s12967-023-04101-x. J Transl Med. 2023. PMID: 37143061 Free PMC article.
The First-In-Class Anti-AXL×CD3ε Pronectin™-Based Bispecific T-Cell Engager Is Active in Preclinical Models of Human Soft Tissue and Bone Sarcomas.
Polerà N, Mancuso A, Riillo C, Caracciolo D, Signorelli S, Grillone K, Ascrizzi S, Hokanson CA, Conforti F, Staropoli N, Gervasi L, Di Martino MT, Arbitrio M, Nisticò G, Crea R, Tagliaferri P, Juli G, Tassone P. Polerà N, et al. Among authors: ascrizzi s. Cancers (Basel). 2023 Mar 8;15(6):1647. doi: 10.3390/cancers15061647. Cancers (Basel). 2023. PMID: 36980534 Free PMC article.
TERRA G-quadruplex stabilization as a new therapeutic strategy for multiple myeloma.
Scionti F, Juli G, Rocca R, Polerà N, Nadai M, Grillone K, Caracciolo D, Riillo C, Altomare E, Ascrizzi S, Caparello B, Cerra M, Arbitrio M, Richter SN, Artese A, Alcaro S, Tagliaferri P, Tassone P, Di Martino MT. Scionti F, et al. Among authors: ascrizzi s. J Exp Clin Cancer Res. 2023 Mar 27;42(1):71. doi: 10.1186/s13046-023-02633-0. J Exp Clin Cancer Res. 2023. PMID: 36967378 Free PMC article.
12 results