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A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.
El Zawily A, Vizeacoumar FS, Dahiya R, Banerjee SL, Bhanumathy KK, Elhasasna H, Hanover G, Sharpe JC, Sanchez MG, Greidanus P, Stacey RG, Moon KM, Alexandrov I, Himanen JP, Nikolov DB, Fonge H, White AP, Foster LJ, Wang B, Toosi BM, Bisson N, Mirzabekov TA, Vizeacoumar FJ, Freywald A. El Zawily A, et al. Among authors: toosi bm. Clin Cancer Res. 2023 Jul 14;29(14):2686-2701. doi: 10.1158/1078-0432.CCR-22-2535. Clin Cancer Res. 2023. PMID: 36976175 Free PMC article.
EPHB6 augments both development and drug sensitivity of triple-negative breast cancer tumours.
Toosi BM, El Zawily A, Truitt L, Shannon M, Allonby O, Babu M, DeCoteau J, Mousseau D, Ali M, Freywald T, Gall A, Vizeacoumar FS, Kirzinger MW, Geyer CR, Anderson DH, Kim T, Welm AL, Siegel P, Vizeacoumar FJ, Kusalik A, Freywald A. Toosi BM, et al. Oncogene. 2018 Jul;37(30):4073-4093. doi: 10.1038/s41388-018-0228-x. Epub 2018 Apr 27. Oncogene. 2018. PMID: 29700392 Free PMC article.
Molecular characterization of an MLL1 fusion and its role in chromosomal instability.
Parameswaran S, Vizeacoumar FS, Kalyanasundaram Bhanumathy K, Qin F, Islam MF, Toosi BM, Cunningham CE, Mousseau DD, Uppalapati MC, Stirling PC, Wu Y, Bonham K, Freywald A, Li H, Vizeacoumar FJ. Parameswaran S, et al. Among authors: toosi bm. Mol Oncol. 2019 Feb;13(2):422-440. doi: 10.1002/1878-0261.12423. Epub 2018 Dec 31. Mol Oncol. 2019. PMID: 30548174 Free PMC article.
The EphB6 Receptor: Kinase-Dead but Very Much Alive.
Strozen TG, Sharpe JC, Harris ED, Uppalapati M, Toosi BM. Strozen TG, et al. Among authors: toosi bm. Int J Mol Sci. 2021 Jul 30;22(15):8211. doi: 10.3390/ijms22158211. Int J Mol Sci. 2021. PMID: 34360976 Free PMC article. Review.
Integration of cancer-related genetic landscape of Eph receptors and ephrins with proteomics identifies a crosstalk between EPHB6 and EGFR.
Hanover G, Vizeacoumar FS, Banerjee SL, Nair R, Dahiya R, Osornio-Hernandez AI, Morales AM, Freywald T, Himanen JP, Toosi BM, Bisson N, Vizeacoumar FJ, Freywald A. Hanover G, et al. Among authors: toosi bm. Cell Rep. 2023 Jul 25;42(7):112670. doi: 10.1016/j.celrep.2023.112670. Epub 2023 Jun 30. Cell Rep. 2023. PMID: 37392382 Free article.
24 results