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Goldilocks and RNA: where Mg2+ concentration is just right.
Guth-Metzler R, Mohamed AM, Cowan ET, Henning A, Ito C, Frenkel-Pinter M, Wartell RM, Glass JB, Williams LD. Guth-Metzler R, et al. Nucleic Acids Res. 2023 May 8;51(8):3529-3539. doi: 10.1093/nar/gkad124. Nucleic Acids Res. 2023. PMID: 36987860 Free PMC article.
A blueprint for academic laboratories to produce SARS-CoV-2 quantitative RT-PCR test kits.
Mascuch SJ, Fakhretaha-Aval S, Bowman JC, Ma MTH, Thomas G, Bommarius B, Ito C, Zhao L, Newnam GP, Matange KR, Thapa HR, Barlow B, Donegan RK, Nguyen NA, Saccuzzo EG, Obianyor CT, Karunakaran SC, Pollet P, Rothschild-Mancinelli B, Mestre-Fos S, Guth-Metzler R, Bryksin AV, Petrov AS, Hazell M, Ibberson CB, Penev PI, Mannino RG, Lam WA, Garcia AJ, Kubanek J, Agarwal V, Hud NV, Glass JB, Williams LD, Lieberman RL. Mascuch SJ, et al. Among authors: guth metzler r. J Biol Chem. 2020 Nov 13;295(46):15438-15453. doi: 10.1074/jbc.RA120.015434. Epub 2020 Sep 3. J Biol Chem. 2020. PMID: 32883809 Free PMC article.
A blueprint for academic labs to produce SARS-CoV-2 RT-qPCR test kits.
Mascuch SJ, Fakhretaha-Aval S, Bowman JC, Ma MTH, Thomas G, Bommarius B, Ito C, Zhao L, Newnam GP, Matange KR, Thapa HR, Barlow B, Donegan RK, Nguyen NA, Saccuzzo EG, Obianyor CT, Karunakaran SC, Pollet P, Rothschild-Mancinelli B, Mestre-Fos S, Guth-Metzler R, Bryksin AV, Petrov AS, Hazell M, Ibberson CB, Penev PI, Mannino RG, Lam WA, Garcia AJ, Kubanek JM, Agarwal V, Hud NV, Glass JB, Williams LD, Lieberman RL. Mascuch SJ, et al. Among authors: guth metzler r. medRxiv [Preprint]. 2020 Sep 1:2020.07.29.20163949. doi: 10.1101/2020.07.29.20163949. medRxiv. 2020. Update in: J Biol Chem. 2020 Nov 13;295(46):15438-15453. doi: 10.1074/jbc.RA120.015434 PMID: 32766604 Free PMC article. Updated. Preprint.
Cutting in-line with iron: ribosomal function and non-oxidative RNA cleavage.
Guth-Metzler R, Bray MS, Frenkel-Pinter M, Suttapitugsakul S, Montllor-Albalate C, Bowman JC, Wu R, Reddi AR, Okafor CD, Glass JB, Williams LD. Guth-Metzler R, et al. Nucleic Acids Res. 2020 Sep 4;48(15):8663-8674. doi: 10.1093/nar/gkaa586. Nucleic Acids Res. 2020. PMID: 32663277 Free PMC article.