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Identification of a Putative α-synuclein Radioligand Using an in silico Similarity Search.
Janssen B, Tian G, Lengyel-Zhand Z, Hsieh CJ, Lougee MG, Riad A, Xu K, Hou C, Weng CC, Lopresti BJ, Kim HJ, Pagar VV, Ferrie JJ, Garcia BA, Mathis CA, Luk K, Petersson EJ, Mach RH. Janssen B, et al. Among authors: luk k. Mol Imaging Biol. 2023 Aug;25(4):704-719. doi: 10.1007/s11307-023-01814-9. Epub 2023 Mar 29. Mol Imaging Biol. 2023. PMID: 36991273 Free PMC article.
α-Synuclein arginylation in the human brain.
Zhao J, Pan B, Fina M, Huang Y, Shimogawa M, Luk KC, Rhoades E, Petersson EJ, Dong DW, Kashina A. Zhao J, et al. Transl Neurodegener. 2022 Apr 8;11(1):20. doi: 10.1186/s40035-022-00295-0. Transl Neurodegener. 2022. PMID: 35395956 Free PMC article.
A Novel Brain PET Radiotracer for Imaging Alpha Synuclein Fibrils in Multiple System Atrophy.
Kim HY, Chia WK, Hsieh CJ, Saturnino Guarino D, Graham TJA, Lengyel-Zhand Z, Schneider M, Tomita C, Lougee MG, Kim HJ, Pagar VV, Lee H, Hou C, Garcia BA, Petersson EJ, O'Shea J, Kotzbauer PT, Mathis CA, Lee VM, Luk KC, Mach RH. Kim HY, et al. J Med Chem. 2023 Sep 14;66(17):12185-12202. doi: 10.1021/acs.jmedchem.3c00779. Epub 2023 Aug 31. J Med Chem. 2023. PMID: 37651366 Free PMC article.
Cell-to-Cell Transmission of Tau and α-Synuclein.
Uemura N, Uemura MT, Luk KC, Lee VM, Trojanowski JQ. Uemura N, et al. Trends Mol Med. 2020 Oct;26(10):936-952. doi: 10.1016/j.molmed.2020.03.012. Epub 2020 May 1. Trends Mol Med. 2020. PMID: 32371172 Free PMC article. Review.
Current insights and assumptions on α-synuclein in Lewy body disease.
Leak RK, Clark RN, Abbas M, Xu F, Brodsky JL, Chen J, Hu X, Luk KC. Leak RK, et al. Among authors: luk kc. Acta Neuropathol. 2024 Aug 14;148(1):18. doi: 10.1007/s00401-024-02781-3. Acta Neuropathol. 2024. PMID: 39141121 Free PMC article. Review.
831 results