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The nucleotide addition cycle of the SARS-CoV-2 polymerase.
Bera SC, Seifert M, Kirchdoerfer RN, van Nies P, Wubulikasimu Y, Quack S, Papini FS, Arnold JJ, Canard B, Cameron CE, Depken M, Dulin D. Bera SC, et al. Among authors: kirchdoerfer rn. bioRxiv [Preprint]. 2021 Mar 27:2021.03.27.437309. doi: 10.1101/2021.03.27.437309. bioRxiv. 2021. Update in: Cell Rep. 2021 Aug 31;36(9):109650. doi: 10.1016/j.celrep.2021.109650 PMID: 33791706 Free PMC article. Updated. Preprint.
Inhibition of SARS-CoV-2 polymerase by nucleotide analogs: a single molecule perspective.
Seifert M, Bera SC, van Nies P, Kirchdoerfer RN, Shannon A, Le TT, Meng X, Xia H, Wood JM, Harris LD, Papini FS, Arnold JJ, Almo SC, Grove TL, Shi PY, Xiang Y, Canard B, Depken M, Cameron CE, Dulin D. Seifert M, et al. Among authors: kirchdoerfer rn. bioRxiv [Preprint]. 2021 Apr 8:2020.08.06.240325. doi: 10.1101/2020.08.06.240325. bioRxiv. 2021. Update in: Elife. 2021 Oct 07;10:e70968. doi: 10.7554/eLife.70968 PMID: 33851161 Free PMC article. Updated. Preprint.
Interfering with nucleotide excision by the coronavirus 3'-to-5' exoribonuclease.
Chinthapatla R, Sotoudegan M, Anderson T, Moustafa IM, Passow KT, Kennelly SA, Moorthy R, Dulin D, Feng JY, Harki DA, Kirchdoerfer R, Cameron CE, Arnold JJ. Chinthapatla R, et al. bioRxiv [Preprint]. 2022 Aug 11:2022.08.11.503614. doi: 10.1101/2022.08.11.503614. bioRxiv. 2022. Update in: Nucleic Acids Res. 2023 Jan 11;51(1):315-336. doi: 10.1093/nar/gkac1177 PMID: 35982684 Free PMC article. Updated. Preprint.
Role of spike in the pathogenic and antigenic behavior of SARS-CoV-2 BA.1 Omicron.
Chen DY, Kenney D, Chin CV, Tavares AH, Khan N, Conway HL, Liu G, Choudhary MC, Gertje HP, O'Connell AK, Kotton DN, Herrmann A, Ensser A, Connor JH, Bosmann M, Li JZ, Gack MU, Baker SC, Kirchdoerfer RN, Kataria Y, Crossland NA, Douam F, Saeed M. Chen DY, et al. Among authors: kirchdoerfer rn. bioRxiv [Preprint]. 2023 Jan 10:2022.10.13.512134. doi: 10.1101/2022.10.13.512134. bioRxiv. 2023. PMID: 36263066 Free PMC article. Preprint.
Spike and nsp6 are key determinants of SARS-CoV-2 Omicron BA.1 attenuation.
Chen DY, Chin CV, Kenney D, Tavares AH, Khan N, Conway HL, Liu G, Choudhary MC, Gertje HP, O'Connell AK, Adams S, Kotton DN, Herrmann A, Ensser A, Connor JH, Bosmann M, Li JZ, Gack MU, Baker SC, Kirchdoerfer RN, Kataria Y, Crossland NA, Douam F, Saeed M. Chen DY, et al. Among authors: kirchdoerfer rn. Nature. 2023 Mar;615(7950):143-150. doi: 10.1038/s41586-023-05697-2. Epub 2023 Jan 11. Nature. 2023. PMID: 36630998
Interfering with nucleotide excision by the coronavirus 3'-to-5' exoribonuclease.
Chinthapatla R, Sotoudegan M, Srivastava P, Anderson TK, Moustafa IM, Passow KT, Kennelly SA, Moorthy R, Dulin D, Feng JY, Harki DA, Kirchdoerfer RN, Cameron CE, Arnold JJ. Chinthapatla R, et al. Among authors: kirchdoerfer rn. Nucleic Acids Res. 2023 Jan 11;51(1):315-336. doi: 10.1093/nar/gkac1177. Nucleic Acids Res. 2023. PMID: 36546762 Free PMC article.
44 results