Chavez A - Search Results

1

Targeted DNA integration in human cells without double-strand breaks using CRISPR RNA-guided transposases.

Lampe GD, King RT, Halpin-Healy TS, Klompe SE, Hogan MI, Vo PLH, Tang S, Chavez A, Sternberg SH. Lampe GD, et al. Among authors: chavez a. bioRxiv [Preprint]. 2023 Mar 18:2023.03.17.533036. doi: 10.1101/2023.03.17.533036. bioRxiv. 2023. Update in: Nat Biotechnol. 2024 Jan;42(1):87-98. doi: 10.1038/s41587-023-01748-1 PMID: 36993517 Free PMC article. Updated. Preprint.

2

Targeted DNA integration in human cells without double-strand breaks using CRISPR-associated transposases.

Lampe GD, King RT, Halpin-Healy TS, Klompe SE, Hogan MI, Vo PLH, Tang S, Chavez A, Sternberg SH. Lampe GD, et al. Among authors: chavez a. Nat Biotechnol. 2024 Jan;42(1):87-98. doi: 10.1038/s41587-023-01748-1. Epub 2023 Mar 29. Nat Biotechnol. 2024. PMID: 36991112 Free PMC article.

3

Enhanced Bacterial Immunity and Mammalian Genome Editing via RNA-Polymerase-Mediated Dislodging of Cas9 from Double-Strand DNA Breaks.

Clarke R, Heler R, MacDougall MS, Yeo NC, Chavez A, Regan M, Hanakahi L, Church GM, Marraffini LA, Merrill BJ. Clarke R, et al. Among authors: chavez a. Mol Cell. 2018 Jul 5;71(1):42-55.e8. doi: 10.1016/j.molcel.2018.06.005. Mol Cell. 2018. PMID: 29979968 Free PMC article.

4

Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors.

Iketani S, Forouhar F, Liu H, Hong SJ, Lin FY, Nair MS, Zask A, Huang Y, Xing L, Stockwell BR, Chavez A, Ho DD. Iketani S, et al. Among authors: chavez a. bioRxiv [Preprint]. 2020 Aug 4:2020.08.03.235291. doi: 10.1101/2020.08.03.235291. bioRxiv. 2020. Update in: Nat Commun. 2021 Apr 1;12(1):2016. doi: 10.1038/s41467-021-22362-2 PMID: 32793898 Free PMC article. Updated. Preprint.

5

A simplified cell-based assay to identify coronavirus 3CL protease inhibitors.

Resnick SJ, Iketani S, Hong SJ, Zask A, Liu H, Kim S, Melore S, Nair MS, Huang Y, Tay NES, Rovis T, Yang HW, Stockwell BR, Ho DD, Chavez A. Resnick SJ, et al. Among authors: chavez a. bioRxiv [Preprint]. 2020 Aug 29:2020.08.29.272864. doi: 10.1101/2020.08.29.272864. bioRxiv. 2020. PMID: 32869020 Free PMC article. Preprint.

6

Development and applications of a CRISPR activation system for facile genetic overexpression in Candida albicans.

Gervais NC, La Bella AA, Wensing LF, Sharma J, Acquaviva V, Best M, Cadena López RO, Fogal M, Uthayakumar D, Chavez A, Santiago-Tirado F, Flores-Mireles AL, Shapiro RS. Gervais NC, et al. Among authors: chavez a. G3 (Bethesda). 2023 Feb 9;13(2):jkac301. doi: 10.1093/g3journal/jkac301. G3 (Bethesda). 2023. PMID: 36450451 Free PMC article.

7

A CRISPR-Cas9-based gene drive platform for genetic interaction analysis in Candida albicans.

Shapiro RS, Chavez A, Porter CBM, Hamblin M, Kaas CS, DiCarlo JE, Zeng G, Xu X, Revtovich AV, Kirienko NV, Wang Y, Church GM, Collins JJ. Shapiro RS, et al. Among authors: chavez a. Nat Microbiol. 2018 Jan;3(1):73-82. doi: 10.1038/s41564-017-0043-0. Epub 2017 Oct 23. Nat Microbiol. 2018. PMID: 29062088 Free PMC article.

8

Design, execution, and analysis of CRISPR-Cas9-based deletions and genetic interaction networks in the fungal pathogen Candida albicans.

Halder V, Porter CBM, Chavez A, Shapiro RS. Halder V, et al. Among authors: chavez a. Nat Protoc. 2019 Mar;14(3):955-975. doi: 10.1038/s41596-018-0122-6. Epub 2019 Feb 8. Nat Protoc. 2019. PMID: 30737491

9

A CRISPR Interference Platform for Efficient Genetic Repression in Candida albicans.

Wensing L, Sharma J, Uthayakumar D, Proteau Y, Chavez A, Shapiro RS. Wensing L, et al. Among authors: chavez a. mSphere. 2019 Feb 13;4(1):e00002-19. doi: 10.1128/mSphere.00002-19. mSphere. 2019. PMID: 30760609 Free PMC article.

10

Accurate analysis of genuine CRISPR editing events with ampliCan.

Labun K, Guo X, Chavez A, Church G, Gagnon JA, Valen E. Labun K, et al. Among authors: chavez a. Genome Res. 2019 May;29(5):843-847. doi: 10.1101/gr.244293.118. Epub 2019 Mar 8. Genome Res. 2019. PMID: 30850374 Free PMC article.

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