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Protein arginine methyltransferase 5 (PRMT5) is an actionable therapeutic target in CDK4/6 inhibitor-resistant ER+/RB-deficient breast cancer.
Lin CC, Chang TC, Wang Y, Guo L, Gao Y, Bikorimana E, Lemoff A, Fang YV, Zhang H, Zhang Y, Ye D, Soria-Bretones I, Servetto A, Lee KM, Luo X, Otto JJ, Akamatsu H, Napolitano F, Mani R, Cescon DW, Xu L, Xie Y, Mendell JT, Hanker AB, Arteaga CL. Lin CC, et al. Among authors: lemoff a. Res Sq [Preprint]. 2023 Jul 10:rs.3.rs-2966905. doi: 10.21203/rs.3.rs-2966905/v1. Res Sq. 2023. Update in: Nat Commun. 2024 Mar 13;15(1):2287. doi: 10.1038/s41467-024-46495-2 PMID: 37502925 Free PMC article. Updated. Preprint.
VCP regulates early tau seed amplification via specific cofactors.
Batra S, Vaquer-Alicea J, Valdez C, Taylor SP, Manon VA, Vega AR, Kashmer OM, Kolay S, Lemoff A, Cairns NJ, White CL 3rd, Diamond MI. Batra S, et al. Among authors: lemoff a. Mol Neurodegener. 2025 Jan 7;20(1):2. doi: 10.1186/s13024-024-00783-z. Mol Neurodegener. 2025. PMID: 39773263 Free PMC article.
The interplay of quaternary ammonium lipid structure and protein corona on lung-specific mRNA delivery by selective organ targeting (SORT) nanoparticles.
Dilliard SA, Sun Y, Brown MO, Sung YC, Chatterjee S, Farbiak L, Vaidya A, Lian X, Wang X, Lemoff A, Siegwart DJ. Dilliard SA, et al. Among authors: lemoff a. J Control Release. 2023 Sep;361:361-372. doi: 10.1016/j.jconrel.2023.07.058. Epub 2023 Aug 10. J Control Release. 2023. PMID: 37536547 Free PMC article.
UBE2J1 is the E2 ubiquitin-conjugating enzyme regulating androgen receptor degradation and antiandrogen resistance.
Rodriguez Tirado C, Wang C, Li X, Deng S, Gonzalez J, Johnson NA, Xu Y, Metang LA, Sundar Rajan M, Yang Y, Yin Y, Hofstad M, Raj GV, Zhang S, Lemoff A, He W, Fan J, Wang Y, Wang T, Mu P. Rodriguez Tirado C, et al. Among authors: lemoff a. Oncogene. 2024 Jan;43(4):265-280. doi: 10.1038/s41388-023-02890-5. Epub 2023 Nov 29. Oncogene. 2024. PMID: 38030789 Free PMC article.
Iron acquisition by a commensal bacterium modifies host nutritional immunity during Salmonella infection.
Spiga L, Fansler RT, Perera YR, Shealy NG, Munneke MJ, David HE, Torres TP, Lemoff A, Ran X, Richardson KL, Pudlo N, Martens EC, Folta-Stogniew E, Yang ZJ, Skaar EP, Byndloss MX, Chazin WJ, Zhu W. Spiga L, et al. Among authors: lemoff a. Cell Host Microbe. 2023 Oct 11;31(10):1639-1654.e10. doi: 10.1016/j.chom.2023.08.018. Epub 2023 Sep 29. Cell Host Microbe. 2023. PMID: 37776864 Free PMC article.
61 results