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Emerging principles of cytokine pharmacology and therapeutics.
Saxton RA, Glassman CR, Garcia KC. Saxton RA, et al. Nat Rev Drug Discov. 2023 Jan;22(1):21-37. doi: 10.1038/s41573-022-00557-6. Epub 2022 Sep 21. Nat Rev Drug Discov. 2023. PMID: 36131080 Free PMC article. Review.
Structural basis of Janus kinase trans-activation.
Caveney NA, Saxton RA, Waghray D, Glassman CR, Tsutsumi N, Hubbard SR, Garcia KC. Caveney NA, et al. Among authors: saxton ra. Cell Rep. 2023 Mar 28;42(3):112201. doi: 10.1016/j.celrep.2023.112201. Epub 2023 Mar 2. Cell Rep. 2023. PMID: 36867534 Free PMC article.
A structural blueprint for interleukin-21 signal modulation.
Abhiraman GC, Bruun TUJ, Caveney NA, Su LL, Saxton RA, Yin Q, Tang S, Davis MM, Jude KM, Garcia KC. Abhiraman GC, et al. Among authors: saxton ra. Cell Rep. 2023 Jun 27;42(6):112657. doi: 10.1016/j.celrep.2023.112657. Epub 2023 Jun 19. Cell Rep. 2023. PMID: 37339051 Free PMC article.
Structure of the interleukin-5 receptor complex exemplifies the organizing principle of common beta cytokine signaling.
Caveney NA, Rodriguez GE, Pollmann C, Meyer T, Borowska MT, Wilson SC, Wang N, Xiang X, Householder KD, Tao P, Su LL, Saxton RA, Piehler J, Garcia KC. Caveney NA, et al. Among authors: saxton ra. Mol Cell. 2024 May 16;84(10):1995-2005.e7. doi: 10.1016/j.molcel.2024.03.023. Epub 2024 Apr 12. Mol Cell. 2024. PMID: 38614096 Free article.
22 results