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A Potential Boron Neutron Capture Therapy Agent Selectively Suppresses High-Grade Glioma: In Vitro and in Vivo Exploration.
Alamón C, Dávila B, García MF, Nievas S, Dagrosa MA, Thorp S, Kovacs M, Trias E, Faccio R, Gabay M, Zeineh N, Weizman A, Teixidor F, Viñas C, Gavish M, Cerecetto H, Couto M. Alamón C, et al. Among authors: gabay m. Mol Pharm. 2023 May 1;20(5):2702-2713. doi: 10.1021/acs.molpharmaceut.3c00152. Epub 2023 Apr 4. Mol Pharm. 2023. PMID: 37013916
Sunitinib-Containing Carborane Pharmacophore with the Ability to Inhibit Tyrosine Kinases Receptors FLT3, KIT and PDGFR-β, Exhibits Powerful In Vivo Anti-Glioblastoma Activity.
Alamón C, Dávila B, García MF, Sánchez C, Kovacs M, Trias E, Barbeito L, Gabay M, Zeineh N, Gavish M, Teixidor F, Viñas C, Couto M, Cerecetto H. Alamón C, et al. Among authors: gabay m. Cancers (Basel). 2020 Nov 18;12(11):3423. doi: 10.3390/cancers12113423. Cancers (Basel). 2020. PMID: 33218150 Free PMC article.
Identification of a new amide-containing thiazole as a drug candidate for treatment of Chagas' disease.
Álvarez G, Varela J, Cruces E, Fernández M, Gabay M, Leal SM, Escobar P, Sanabria L, Serna E, Torres S, Figueredo Thiel SJ, Yaluff G, Vera de Bilbao NI, Cerecetto H, González M. Álvarez G, et al. Among authors: gabay m. Antimicrob Agents Chemother. 2015 Mar;59(3):1398-404. doi: 10.1128/AAC.03814-14. Epub 2014 Dec 15. Antimicrob Agents Chemother. 2015. PMID: 25512408 Free PMC article.
Development of bis-thiazoles as inhibitors of triosephosphate isomerase from Trypanosoma cruzi. Identification of new non-mutagenic agents that are active in vivo.
Álvarez G, Martínez J, Varela J, Birriel E, Cruces E, Gabay M, Leal SM, Escobar P, Aguirre-López B, Cabrera N, Tuena de Gómez-Puyou M, Gómez Puyou A, Pérez-Montfort R, Yaluff G, Torres S, Serna E, Vera de Bilbao N, González M, Cerecetto H. Álvarez G, et al. Among authors: gabay m. Eur J Med Chem. 2015 Jul 15;100:246-56. doi: 10.1016/j.ejmech.2015.06.018. Epub 2015 Jun 12. Eur J Med Chem. 2015. PMID: 26094151
Optimization of antitrypanosomatid agents: identification of nonmutagenic drug candidates with in vivo activity.
Álvarez G, Varela J, Márquez P, Gabay M, Arias Rivas CE, Cuchilla K, Echeverría GA, Piro OE, Chorilli M, Leal SM, Escobar P, Serna E, Torres S, Yaluff G, Vera de Bilbao NI, González M, Cerecetto H. Álvarez G, et al. Among authors: gabay m. J Med Chem. 2014 May 22;57(10):3984-99. doi: 10.1021/jm500018m. Epub 2014 May 2. J Med Chem. 2014. PMID: 24749923
130 results