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The unfolded protein response transcription factor XBP1s ameliorates Alzheimer's disease by improving synaptic function and proteostasis.
Duran-Aniotz C, Poblete N, Rivera-Krstulovic C, Ardiles ÁO, Díaz-Hung ML, Tamburini G, Sabusap CMP, Gerakis Y, Cabral-Miranda F, Diaz J, Fuentealba M, Arriagada D, Muñoz E, Espinoza S, Martinez G, Quiroz G, Sardi P, Medinas DB, Contreras D, Piña R, Lourenco MV, Ribeiro FC, Ferreira ST, Rozas C, Morales B, Plate L, Gonzalez-Billault C, Palacios AG, Hetz C. Duran-Aniotz C, et al. Among authors: contreras d. Mol Ther. 2023 Jul 5;31(7):2240-2256. doi: 10.1016/j.ymthe.2023.03.028. Epub 2023 Apr 4. Mol Ther. 2023. PMID: 37016577 Free PMC article.
Single and Repeated Administration of Methylphenidate Modulates Synaptic Plasticity in Opposite Directions via Insertion of AMPA Receptors in Rat Hippocampal Neurons.
Carvallo C, Contreras D, Ugarte G, Delgado R, Pancetti F, Rozas C, Piña R, Constandil L, Zeise ML, Morales B. Carvallo C, et al. Among authors: contreras d. Front Pharmacol. 2018 Dec 19;9:1485. doi: 10.3389/fphar.2018.01485. eCollection 2018. Front Pharmacol. 2018. PMID: 30618772 Free PMC article.
Mutation in protein disulfide isomerase A3 causes neurodevelopmental defects by disturbing endoplasmic reticulum proteostasis.
Bilches Medinas D, Malik S, Yıldız-Bölükbaşı E, Borgonovo J, Saaranen MJ, Urra H, Pulgar E, Afzal M, Contreras D, Wright MT, Bodaleo F, Quiroz G, Rozas P, Mumtaz S, Díaz R, Rozas C, Cabral-Miranda F, Piña R, Valenzuela V, Uyan O, Reardon C, Woehlbier U, Brown RH, Sena-Esteves M, Gonzalez-Billault C, Morales B, Plate L, Ruddock LW, Concha ML, Hetz C, Tolun A. Bilches Medinas D, et al. Among authors: contreras d. EMBO J. 2022 Dec 17;41(2):e105531. doi: 10.15252/embj.2020105531. Epub 2021 Dec 14. EMBO J. 2022. PMID: 34904718 Free PMC article.
Methylphenidate Restores Behavioral and Neuroplasticity Impairments in the Prenatal Nicotine Exposure Mouse Model of ADHD: Evidence for Involvement of AMPA Receptor Subunit Composition and Synaptic Spine Morphology in the Hippocampus.
Contreras D, Piña R, Carvallo C, Godoy F, Ugarte G, Zeise M, Rozas C, Morales B. Contreras D, et al. Int J Mol Sci. 2022 Jun 26;23(13):7099. doi: 10.3390/ijms23137099. Int J Mol Sci. 2022. PMID: 35806103 Free PMC article.
Ketogenic diet administration later in life improves memory by modifying the synaptic cortical proteome via the PKA signaling pathway in aging mice.
Acuña-Catalán D, Shah S, Wehrfritz C, Nomura M, Acevedo A, Olmos C, Quiroz G, Huerta H, Bons J, Ampuero E, Wyneken U, Sanhueza M, Arancibia F, Contreras D, Cárdenas JC, Morales B, Schilling B, Newman JC, González-Billault C. Acuña-Catalán D, et al. Among authors: contreras d. Cell Rep Med. 2024 Jun 18;5(6):101593. doi: 10.1016/j.xcrm.2024.101593. Epub 2024 Jun 5. Cell Rep Med. 2024. PMID: 38843842 Free PMC article.
329 results