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An early, reversible cholesterolgenic etiology of diet-induced insulin resistance.
Covert JD, Grice BA, Thornburg MG, Kaur M, Ryan AP, Tackett L, Bhamidipati T, Stull ND, Kim T, Habegger KM, McClain DA, Brozinick JT, Elmendorf JS. Covert JD, et al. Mol Metab. 2023 Jun;72:101715. doi: 10.1016/j.molmet.2023.101715. Epub 2023 Apr 3. Mol Metab. 2023. PMID: 37019209 Free PMC article.
Excess membrane cholesterol is an early contributing reversible aspect of skeletal muscle insulin resistance in C57BL/6NJ mice fed a Western-style high-fat diet.
Grice BA, Barton KJ, Covert JD, Kreilach AM, Tackett L, Brozinick JT, Elmendorf JS. Grice BA, et al. Among authors: covert jd. Am J Physiol Endocrinol Metab. 2019 Aug 1;317(2):E362-E373. doi: 10.1152/ajpendo.00396.2018. Epub 2019 Jun 25. Am J Physiol Endocrinol Metab. 2019. PMID: 31237447 Free PMC article.