Orfila JE - Search Results

1

Short-term CaMKII inhibition with tatCN19o does not erase pre-formed memory in mice and is neuroprotective in pigs.

Rumian NL, Brown CN, Hendry-Hofer TB, Rossetti T, Orfila JE, Tullis JE, Dwoskin LP, Buonarati OR, Lisman JE, Quillinan N, Herson PS, Bebarta VS, Bayer KU. Rumian NL, et al. Among authors: orfila je. J Biol Chem. 2023 May;299(5):104693. doi: 10.1016/j.jbc.2023.104693. Epub 2023 Apr 8. J Biol Chem. 2023. PMID: 37037305 Free PMC article.

2

Increasing small conductance Ca2+-activated potassium channel activity reverses ischemia-induced impairment of long-term potentiation.

Orfila JE, Shimizu K, Garske AK, Deng G, Maylie J, Traystman RJ, Quillinan N, Adelman JP, Herson PS. Orfila JE, et al. Eur J Neurosci. 2014 Oct;40(8):3179-88. doi: 10.1111/ejn.12683. Epub 2014 Jul 31. Eur J Neurosci. 2014. PMID: 25080203 Free PMC article.

3

Sirtuin-2 mediates male specific neuronal injury following experimental cardiac arrest through activation of TRPM2 ion channels.

Shimizu K, Quillinan N, Orfila JE, Herson PS. Shimizu K, et al. Among authors: orfila je. Exp Neurol. 2016 Jan;275 Pt 1(Pt 1):78-83. doi: 10.1016/j.expneurol.2015.10.014. Epub 2015 Oct 30. Exp Neurol. 2016. PMID: 26522013 Free PMC article.

4

Therapeutic hypothermia protects against ischemia-induced impairment of synaptic plasticity following juvenile cardiac arrest in sex-dependent manner.

Dietz RM, Deng G, Orfila JE, Hui X, Traystman RJ, Herson PS. Dietz RM, et al. Among authors: orfila je. Neuroscience. 2016 Jun 14;325:132-41. doi: 10.1016/j.neuroscience.2016.03.052. Epub 2016 Mar 29. Neuroscience. 2016. PMID: 27033251 Free PMC article.

5

Autonomous CaMKII Activity as a Drug Target for Histological and Functional Neuroprotection after Resuscitation from Cardiac Arrest.

Deng G, Orfila JE, Dietz RM, Moreno-Garcia M, Rodgers KM, Coultrap SJ, Quillinan N, Traystman RJ, Bayer KU, Herson PS. Deng G, et al. Among authors: orfila je. Cell Rep. 2017 Jan 31;18(5):1109-1117. doi: 10.1016/j.celrep.2017.01.011. Cell Rep. 2017. PMID: 28147268 Free PMC article.

6

The role of T-type calcium channels in the subiculum: to burst or not to burst?

Joksimovic SM, Eggan P, Izumi Y, Joksimovic SL, Tesic V, Dietz RM, Orfila JE, DiGruccio MR, Herson PS, Jevtovic-Todorovic V, Zorumski CF, Todorovic SM. Joksimovic SM, et al. Among authors: orfila je. J Physiol. 2017 Oct 1;595(19):6327-6348. doi: 10.1113/JP274565. Epub 2017 Aug 18. J Physiol. 2017. PMID: 28744923 Free PMC article.

7

Delayed inhibition of tonic inhibition enhances functional recovery following experimental ischemic stroke.

Orfila JE, Grewal H, Dietz RM, Strnad F, Shimizu T, Moreno M, Schroeder C, Yonchek J, Rodgers KM, Dingman A, Bernard TJ, Quillinan N, Macklin WB, Traystman RJ, Herson PS. Orfila JE, et al. J Cereb Blood Flow Metab. 2019 Jun;39(6):1005-1014. doi: 10.1177/0271678X17750761. Epub 2017 Dec 28. J Cereb Blood Flow Metab. 2019. PMID: 29283314 Free PMC article.

8

Endogenous Sex Steroids Dampen Neuroinflammation and Improve Outcome of Traumatic Brain Injury in Mice.

Clevenger AC, Kim H, Salcedo E, Yonchek JC, Rodgers KM, Orfila JE, Dietz RM, Quillinan N, Traystman RJ, Herson PS. Clevenger AC, et al. Among authors: orfila je. J Mol Neurosci. 2018 Mar;64(3):410-420. doi: 10.1007/s12031-018-1038-x. Epub 2018 Feb 15. J Mol Neurosci. 2018. PMID: 29450697 Free PMC article.

9

Juvenile cerebral ischemia reveals age-dependent BDNF-TrkB signaling changes: Novel mechanism of recovery and therapeutic intervention.

Dietz RM, Orfila JE, Rodgers KM, Patsos OP, Deng G, Chalmers N, Quillinan N, Traystman RJ, Herson PS. Dietz RM, et al. Among authors: orfila je. J Cereb Blood Flow Metab. 2018 Dec;38(12):2223-2235. doi: 10.1177/0271678X18766421. Epub 2018 Apr 3. J Cereb Blood Flow Metab. 2018. PMID: 29611441 Free PMC article.

10

Cardiac Arrest Induces Ischemic Long-Term Potentiation of Hippocampal CA1 Neurons That Occludes Physiological Long-Term Potentiation.

Orfila JE, McKinnon N, Moreno M, Deng G, Chalmers N, Dietz RM, Herson PS, Quillinan N. Orfila JE, et al. Neural Plast. 2018 Apr 26;2018:9275239. doi: 10.1155/2018/9275239. eCollection 2018. Neural Plast. 2018. PMID: 29853851 Free PMC article.

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