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Translational relevance of SOS1 targeting for KRAS-mutant colorectal cancer.
Alem D, Yang X, Beato F, Sarcar B, Tassielli AF, Dai R, Hogenson TL, Park MA, Jiang K, Cai J, Yuan Y, Fernandez-Zapico ME, Tan AC, Fleming JB, Xie H. Alem D, et al. Among authors: xie h. Mol Carcinog. 2023 Jul;62(7):1025-1037. doi: 10.1002/mc.23543. Epub 2023 Apr 12. Mol Carcinog. 2023. PMID: 37042566 Free PMC article.
Culture media composition influences patient-derived organoid ability to predict therapeutic responses in gastrointestinal cancers.
Hogenson TL, Xie H, Phillips WJ, Toruner MD, Li JJ, Horn IP, Kennedy DJ, Almada LL, Marks DL, Carr RM, Toruner M, Sigafoos AN, Koenig-Kappes AN, Olson RL, Tolosa EJ, Zhang C, Li H, Doles JD, Bleeker J, Barrett MT, Boyum JH, Kipp BR, Mahipal A, Hubbard JM, Scheffler Hanson TJ, Petersen GM, Dasari S, Oberg AL, Truty MJ, Graham RP, Levy MJ, Zhu M, Billadeau DD, Adjei AA, Dusetti N, Iovanna JL, Bekaii-Saab TS, Ma WW, Fernandez-Zapico ME. Hogenson TL, et al. Among authors: xie h. JCI Insight. 2022 Nov 22;7(22):e158060. doi: 10.1172/jci.insight.158060. JCI Insight. 2022. PMID: 36256477 Free PMC article.
Development of SOS1 Inhibitor-Based Degraders to Target KRAS-Mutant Colorectal Cancer.
Bian Y, Alem D, Beato F, Hogenson TL, Yang X, Jiang K, Cai J, Ma WW, Fernandez-Zapico M, Tan AC, Lawrence NJ, Fleming JB, Yuan Y, Xie H. Bian Y, et al. Among authors: xie h. J Med Chem. 2022 Dec 22;65(24):16432-16450. doi: 10.1021/acs.jmedchem.2c01300. Epub 2022 Dec 2. J Med Chem. 2022. PMID: 36459180 Free PMC article.
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