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Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination.
Stefanelli I, Corona A, Cerchia C, Cassese E, Improta S, Costanzi E, Pelliccia S, Morasso S, Esposito F, Paulis A, Scognamiglio S, Di Leva FS, Storici P, Brindisi M, Tramontano E, Cannalire R, Summa V. Stefanelli I, et al. Among authors: tramontano e. Eur J Med Chem. 2023 May 5;253:115311. doi: 10.1016/j.ejmech.2023.115311. Epub 2023 Mar 31. Eur J Med Chem. 2023. PMID: 37043904 Free PMC article.
Identification of the amino acid in the human immunodeficiency virus type 1 reverse transcriptase involved in the pyrophosphate binding of antiviral nucleoside triphosphate analogs and phosphonoformate. Implications for multiple drug resistance.
Im GJ, Tramontano E, Gonzalez CJ, Cheng YC. Im GJ, et al. Among authors: tramontano e. Biochem Pharmacol. 1993 Dec 14;46(12):2307-13. doi: 10.1016/0006-2952(93)90622-4. Biochem Pharmacol. 1993. PMID: 7506027 Free article.
177 results